Ulinastatin for acute lung injury and acute respiratory distress syndrome: A systematic review and meta-analysis

Figure 1 Flow chart of reviewed articles. RCT: Randomized controlled trial; NPPV: Noninvasive positive-pressure ventilation; ICU: Intensive care unit.

Figure 2 Oxygenation indexes of different groups before and after treatment. The horizontal axis, number of references.

Figure 3 Meta-analysis of patients’ oxygenation index (A) and intensive care unit mortality rate (B) after treatment with conventional therapy vs with ulinastatin (random effects). A: Random effects model; B: Fixed effects model.

Figure 4 Meta-analysis of 28-d mortality rate (A) and length of intensive care unit stay (B) between treatment with conventional therapy and with ulinastatin. A: Fixed effects model; B: Random effects model.

Figure 5 Funnel plots of intensive care unit mortality (A) and oxygenation index (B). SMD: Standard mean difference.