Evidence Review
Copyright ©The Author(s) 2025.
World J Surg Proced. Jul 16, 2025; 15(2): 109348
Published online Jul 16, 2025. doi: 10.5412/wjsp.v15.i2.109348
Table 1 Summary of key comparative trials and meta-analyses
Ref.
Study type
Comparison groups
Key comparative findings
Additional contributions in current review
Cemil et al[1], 2024 Comparative StudyLHP vs Milligan-Morgan (Grade II/III)Lower pain scores, faster return to workReferenced in pain and operative time outcomes
Wee et al[2], 2023 Meta-analysisLHP vs conventional hemorrhoidectomyLower pain (24 hours, 7 days, 14 days), shorter recoveryMain data source for comparative meta-analysis
Poskus et al[3], 2020 RCTLHP vs sutured mucopexy vs excisionLess pain early on; recurrence higher with LHPUsed to demonstrate recurrence concern
Cheng et al[4], 2024 Meta-analysisDiode LHP vs MM & FergusonLower pain, shorter hospital staySupported benefits in hospital stay and pain
Lie et al[5], 2022Meta-analysisLHP vs Various ControlsLess pain, faster recovery; recurrence concernsCited in recurrence and long-term efficacy debate
Jin et al[6], 2024RCTLHP vs RBL (Grade II)LHP less painful; similar short-term efficacyHighlighted minimally invasive alternative to RBL
Eray et al[7], 2025 Retrospective StudyLHP + Ferguson vs conventionalCombined technique reduced pain and bleedingIntroduced vessel ligation adjunct concept
Maloku et al[8], 2014 Comparative Clinical StudyLHP vs Open HemorrhoidectomyShorter OR time, less postoperative painProvided real-world timing and pain data
Tan et al[9], 2022 Systematic Review & Meta-analysisLHP vs milligan-morgan hemorrhoidectomyLHP had lower pain, bleeding, faster recoveryFramed entire evidence base; critical meta-analysis