Minireviews
Copyright ©2014 Baishideng Publishing Group Inc.
World J Immunol. Nov 27, 2014; 4(3): 185-193
Published online Nov 27, 2014. doi: 10.5411/wji.v4.i3.185
Table 1 Major marker of monocyte subsets
MarkersClassical monocytesIntermediatemonocytesNonclassical-monocytesRef.
CD14+++++[1]
CD16-++[1]
CD86+++++[17]
CD64++++[17]
HLA-AB++++[21]
HLA-DR++++[21,25]
CCR1+++-[21]
CCR2++--[15,20,21]
CCR5+++-[15,20,21]
CXCR1++--[21]
CXCR2++--[15,21]
CX3CR1+++-[15,20]
CD62L++--[20,21]
Table 2 Functional characteristics of monocyte subsets
FunctionsClassicalmonocytesIntermediatemonocytesNonclassical-monocytesRef.
Phagocytosis+++++[25]
MHC II processing++++[25]
Antigen presentation++++[25]
CD4+ T cell proliferation++++[25]
Transendothelial migration--++[15]
Patrolling endothelium--++[24]
Virus sensing--++[24]
TNF production+-++[24]
IL-1β production+++++[24]
CCL2 production++--[24]
IL-10 production++--[24]