Non-esophageal eosinophilic gastrointestinal disease and chronic abdominal pain in children: A multicenter experience

Table 1 Clinical and laboratory features of children with eosinophilic gastrointestinal disease, n (%)

Type of eosinophilic gastrointestinal disease	Characteristic features	Total	Gastric/ duodenal disease [3 (16)]	Ileal disease [3 (16)]	Colonic disease [7 (37)]	Ileocolonic [5 (26)]	Pan gastrointestinal [1 (5)]	P value
Pain abdomen	Epigastric pain	4 (21)	2	3	1	0	1	NS
	Periumbilical	12 (63.2)	1	2	5	3	1	NS
	Lower abdomen	11 (58)	0	0	6	3	0	NS
Diarrhea	Chronic diarrhea	4 (21)	1	2	1	0	0	NS
	Bloody diarrhea	7 (37)	0	0	5	2	0	NS
Atopy	Atopy in patient	8 (42)	1	1	3	2	1	NS
	F/H of atopy	11 (58)	2	2	3	3	1	< 0.00001
Laboratory features	Anemia	8 (42)	2	1	5	2	0
	Hypoalbuminemia (< 3 mg/dL)	4 (21)	2	1	0	1	0
	Peripheral eosinophilia (> 500 cells/dL)	10 (53)	2	2	4	1	1	< 0.00001
	Raised serum immunoglobulin E (> 200 iu/mL)	16 (84)		3	6	4	1	< 0.00001

F/H: Family history; NS: No significance.

Table 2 Endoscopic features of the children with eosinophilic gastrointestinal disease, n (%)

Type of eosinophilic gastro-intestinal disease	Characteristic features	Total (n = 19)	Gastric/duodenal disease [3 (16)]	Ileal disease [3 (16)]	Colonic disease [7 (37)]	Ileocolonic [5 (26)]	Pan gastrointestinal [1 (5)]
Endoscopic appearance	Normal	5 (26)	1		3		1
	Gastric erythema and/or ulcers	5 (26)	2		2		1
	Duodenal LNH	7 (37)	3	1	2	1
	Colonic ulcers	10 (53)			5	5
	Ileal LNH and/or ulcers	6 (32)	0	3		2	1

LNH: Lymphoid nodular hyperplasia.