Fecal calprotectin in pediatric gastrointestinal diseases: Pros and cons

Figure 1  The flow chart of the included studies.

Figure 2 Diagrammatic representation of calprotectin dimer. The crystal two S100A8-S100A9 Dimer structure of calprotectin loaded with Mn²⁺ and Ca²⁺. The black and blue chains represent S100A8 and S100A9, respectively. Purple spheres represent Mn²⁺ and green spheres represent Ca²⁺. Only one manganese ion can bind per calprotectin dimer.