Unique presentation of neonatal liver failure: A case report

Figure 1 The liver biopsy. A: The liver biopsy shows prominent histiocytic proliferation between the portal areas (hematoxylin and eosin, × 100); B: The proliferating cells are diffusely positive for CD68 (a histiocytic marker) (CD68 stain, × 100); C: The cells are negative for hepPar confirming the absence of hepatocytes ( × 100); D: Iron stain shows mild iron deposition in the proliferating ductules and histiocytes (iron stain, × 200).

Figure 2  Electron microscopy highlights the presence of abundant histiocytes (highlighted by arrows) with no hepatocytes.