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World J Ophthalmol. Aug 12, 2014; 4(3): 47-51
Published online Aug 12, 2014. doi: 10.5318/wjo.v4.i3.47
Figure 1
Figure 1 Representative examples of normal, Alzheimer’s disease and Alzheimer’s disease-like cerebral perfusion patterns by SPECT images (sagittal sections and 3D images). A: Normal pattern; B: AD pattern; C: AD-like pattern. Arrows indicate decreased CBF; D: Comparison of relative CBF in the parietal lobe between NTG patients and controls. aP = 0.02, paired t-test; E: Classification of cerebral perfusion patterns by SPECT images in 64 patients with NTG. AD: Alzheimer’s disease; NTG: Normal tension glaucoma; CBF: Cerebral blood flow.
Figure 2
Figure 2 Changes in the cerebral blood flow of the temporal and parietal lobes (A), blood flow in the optic nerve head (C), and mean deviation (D) for each normal tension glaucoma patient after 6 mo of donepezil treatment, a representative change of SPECT images after 6 mo treatment (B). Arrows indicate obviously decreased CBF. ONH blood flow was evaluated by laser speckle flowgraphy, and the MD was obtained by the Humphrey visual field test (program 30-2). aP < 0.05, bP < 0.01 vs pretreatment, paired t-test. ONH: Optic nerve head; MD: Mean deviation; CBF: Cerebral blood flow.