Is nitric oxide level affected in postmenopausal women with hypothyroidism?

Table 1 Comparison of various parameters among postmenopausal hypothyroid (group A) and postmenopausal euthyroid (group B) females

Parameters	Group A	Group B	P value
Body mass index (kg/m2)	30.37 ± 3.26	29.03 ± 3.56	0.993
TSH (μIU/mL)	9.596 ± 2.349 (5.9-15.5)	3.663 ± 1.193 (0.94-4.4)	< 0.001
S. T4 (ng/mL)	1.262 ± 0.707 (0.93-2.1)	6.405 ± 1.727 (3.2-9.2)	< 0.001
S. T3 (ng/mL)	56.266 ± 15.72 (22-77)	98.433 ± 9.640 (85-111)	< 0.001
FT3 (pg/dL)	0.493 ± 0.180 (0.09-0.83)	1.230 ± 0.213 (2.1-4.1)	< 0.001
FT4 (ng/mL)	1.206 ± 0.352 (0.93-2.1)	2.835 ± 0.507 (0.93-1.8))	< 0.001
NO (μmol/L)	25.832 ± 5.286 (16.5-38)	33.671 ± 5.173 (23.16-47)	< 0.001

NO: Nitric oxide; TSH: Thyroid stimulating hormone.

Table 2 Correlation of nitric oxide with different parameters in group A

Parameter	r value	P value
Estrogen	0.21	0.24
Progesterone	-0.14	0.43
TSH	-0.1	0.58
T4	0.36	0.50
T3	0.16	0.38
Free T3	0.22	0.22
Free T4	0.37	0.04

TSH: Thyroid stimulating hormone.

Table 3 Correlation of nitric oxide with different parameters in group B

Parameter	r value	P value
Estrogen	0.13	0.47
Progesterone	-0.06	0.72
TSH	0.00	0.97
T4	0.17	0.36
T3	0.17	0.35
Free T3	0.26	0.15
Free T4	0.31	0.09

TSH: Thyroid stimulating hormone.