High prevalence of post-partum depression in women with coeliac disease

Table 1 Demographic and serological features of patients with coeliac disease and controls

	Group ACeliac women(# 70)	Group BHealthy subjects(# 70)	P value
Mean age (yr)	33.32 ± 2.88	32.32 ± 4.32	0.7
Level of instruction (yr)	11.06 ± 3.54	11.30 ± 3.58	0.9
Hb (gr/dL)	11.03 ± 2.46	11.21 ± 2.54	0.7
Cholesterol (mg/dL)	156.85 ± 35.82	149.68 ± 37.02	0.2
Anti-transglutaminase IgA (U/mL)	< 0.1	< 0.1	0.9
Type of childbirth
Delivery by caesarean section	36/70	31/70	0.7
Vaginal delivery	34/70	39/70	0.7
Outcome of birth
Live birth	70/70	70/70	1.0
Congenital malformations	0/70	1/70	0.9
Number of pregnancies
First pregnancy	34/70	37/70	0.7
Second pregnancy	25/70	24/70	0.9
> 2 pregnancies	11/70	9/70	0.8
Weeks of gestation	37.7 ± 1.78	37.95 ± 1.43	0.9

Table 2 Main results

	Group ACeliac womenn = 70	Group BHealthy subjectsn = 70	P value
EPDS score (mean ± SD)	9.94 ± 5.98	6.7 ± 3.73	< 0.01
Patients with EPDS score ≥ 10 (%)	33/70 (47)	10/70 (14)	< 0.01
PPD after psychiatric assessment	29/33	8/10	0.06
SF-36
PCS (mean ± SD)	55 ± 12	66 ± 8	0.03
MCS (mean ± SD)	43 ± 11	56 ± 7	0.02

EPDS: Edinburgh postnatal depression scale; PPD: Post-partum depression.