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Copyright ©The Author(s) 2015.
World J Obstet Gynecol. Nov 10, 2015; 4(4): 86-94
Published online Nov 10, 2015. doi: 10.5317/wjog.v4.i4.86
Figure 1
Figure 1 Examples of putative diagnostic results identifying carriers of the common β globin gene defects associated with sickle cell disease and β-thalassemia major on different high performance liquid chromatography or capillary electrophoresis devices. From left to right separations on Sebia CE and Bio-Rad, Menarini, Tosoh and Ultra2 HPLC devices. HPLC: High performance liquid chromatography; CE: Capillary electrophoresis; Hb: Hemoglobin.
Figure 2
Figure 2 Typical hemoglobin H inclusion bodies found sporadically in carriers of alpha zero thalassemia (--/αα) and abundantly in patients with hemoglobin H disease (--/-α).
Figure 3
Figure 3 Genetic risk for hemoglobinopathies and practical prevention flow chart after carrier screening early in pregnancy. HPLC: High performance liquid chromatography; CE: Capillary electrophoresis; HBP: Hemoglobinopathy; CBC: Complete blood count.