Molecular pathogenesis of glioblastoma multiforme: Nuances, obstacles, and implications for treatment

doi:10.5316/wjn.v5.i3.88

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Sep 28, 2015 (publication date) through Nov 3, 2024

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World Journal of Neurology

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2218-6212

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Neurol. Sep 28, 2015; 5(3): 88-101
Published online Sep 28, 2015. doi: 10.5316/wjn.v5.i3.88

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Figure 1 Genetic mutations pathways implicated in the development of malignant gliomas (76). WHO: World Health Organization; LOH: Loss of heterozygosity; EGFR: Epidermal growth factor receptor; PTEN: Phosphatase and tensin homolog.

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Figure 2 PTEN locus on chromosome 10. PTEN: Phosphatase and tensin homolog.

Citation: Joshi SK, Lucic N, Zuniga R. Molecular pathogenesis of glioblastoma multiforme: Nuances, obstacles, and implications for treatment. World J Neurol 2015; 5(3): 88-101
URL: https://www.wjgnet.com/2218-6212/full/v5/i3/88.htm
DOI: https://dx.doi.org/10.5316/wjn.v5.i3.88