Helicobacter pylori and inflammatory skin diseases

Table 1 Summary of some of the studies concerned with the association of Helicobacter pylori in the pathogenesis of inflammatory skin diseases, shown in order of publication date

Ref.	Study design	Result
Halasz[21]	Investigation of serum H. pylori IgG antibody titers in 33 psoriatic patients	Suggesting a potential link of H. pylori with psoriasis
Daudén et al[24]	Performing 13C-UBT on 84 patients with psoriasis and 61 patients with lichen planus	Suggesting no evidence of a link between H. pylori and psoriasis and H. pylori and lichen planus
Fabrizi et al[23]	Performing 13C-UBT on 20 psoriatic patients and 29 healthy controls	Suggesting no evidence of a link between H. pylori and psoriasis
Szlachcic[61]	Performing 13C-UBT, CLO-test, oral cavity CLO-test, bacterial culture and fundic biopsy, investigation of serum and saliva H. pylori IgG and IgA antibody titers	Suggesting a potential link of H. pylori with rosacea and improvement of symptoms of rosacea with H. pylori eradication treatment
Qayoom et al[22]	Investigation of serum H. pylori seropositivity in 50 psoriatic patients and healthy controls	Suggesting a potential link of H. pylori with psoriasis
Novák et al[73]	Investigation of serum H. pylori seropositivity in 11 adult HSP and 20 healthy adult patients	Suggesting a potential link of H. pylori with HSP
Shiotani et al[43]	Investigation of serum H. pylori IgG antibody titers in 134 patients with pruritic skin diseases	Suggesting a potential link of H. pylori with pruritic skin diseases and H. pylori positivity in pruritic skin diseased patients with gastric cancer
Moravvej et al[34]	Performing 13C-UBT on 80 patients with lichen planus and 80 patients with other skin diseases	Suggesting a potential link of H. pylori with lichen planus
Ersoy et al[70]	Performing endoscopy, histopathological examination and RUT in 45 patients with BD and 40 healthy controls	Suggesting no evidence of a link between H. pylori and BD
Cakmak et al[68]	Performing 13C-UBT in 40 patients with BD and 40 healthy controls	Suggesting no evidence of a link between H. pylori and BD
El-Khalawany et al[52]	Investigation of serum H. pylori IgG antibody titers and H. pylori stool antigen in 68 patients with rosacea and 54 healthy controls and performing H. pylori genotyping	Suggesting a potential link of H. pylori with rosacea and certain virulent strains with rosacea subtypes
Onsun et al[20]	Investigation of H. pylori stool antigen in 300 psoriatic patients and 150 healthy controls; investigation of H. pylori stool antigen in 25 patients before and after acitretin treatment	Suggesting a potential link of H. pylori with the etiology and the severity of psoriasis
Lankarani et al[69]	Performing 13C-UBT and investigation of H. pylori seropositivity in 48 patients with BD and 48 healthy controls	Suggesting a potential link of H. pylori with BD

H. pylori: Helicobacter pylori; Ig: Immunoglobulin;

¹³C-UBT: ¹³C urea breath test; CLO-test: Campylobacter-like organism test; HSP: Henoch-Schonlein purpura; RUT: Rapid urease test; BD: Behçet’s disease.