Review
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World J Anesthesiol. Mar 27, 2014; 3(1): 46-60
Published online Mar 27, 2014. doi: 10.5313/wja.v3.i1.46
Complex regional pain syndrome: From diagnosis to rehabilitation
Alexandra Lecours, Mathieu Piché
Alexandra Lecours, Mathieu Piché, Department of Chiropractic, Université du Québec à Trois-Rivières, Trois-Rivières G9A 5H7, Québec, Canada
Alexandra Lecours, Department of Occupational Therapy, Université du Québec à Trois-Rivières, Trois-Rivières G9A 5H7, Québec, Canada
Alexandra Lecours, Mathieu Piché, Groupe de Recherche sur les Affections Neuro-musculo-squelettiques, Université du Québec à Trois-Rivières, Trois-Rivières G9A 5H7, Québec, Canada
Alexandra Lecours, Mathieu Piché, Groupe de Recherche en Neuroscience, Université du Québec à Trois-Rivières, Trois-Rivières G9A 5H7, Québec, Canada
Alexandra Lecours, Mathieu Piché, Centre de Recherche en Neuropsychologie et Cognition, Université de Montréal, Montréal H3C 3J7, Québec, Canada
Alexandra Lecours, Mathieu Piché, Centre de recherche de l’Institut universitaire de gériatrie de Montréal, Université de Montréal, Montréal H3C 3J7, Québec, Canada
Author contributions: Lecours A and Piché M contributed to substantial contributions to conception and design, analysis and interpretation of data; Lecours A and Piché M contributed to drafting the article and revising it critically for important intellectual content; and Lecours A and Piché M contributed to final approval of the version to be published.
Supported by Operating grants from the National Science and Engineering Research Council of Canada (MP); the UQTR research chair in pain neurophysiology (MP); and the “Fondation de recherche en chiropratique du Québec” (MP)
Correspondence to: Mathieu Piché, DC, PhD, Associate Professor, Department of Chiropractic, Université du Québec à Trois-Rivières, 3351 boul. des Forges, C.P. 500, Trois-Rivières G9A 5H7, Québec, Canada. mathieu.piché@uqtr.ca
Telephone: +1-819-3765011 Fax: +1-819-3765204
Received: July 29, 2013
Revised: November 16, 2013
Accepted: December 13, 2013
Published online: March 27, 2014
Processing time: 224 Days and 20.7 Hours
Core Tip

Core tip: Complex regional pain syndrome (CRPS) involves a complex pathophysiology including sensory, motor and autonomic disturbances that causes functional disability and reduced quality of life. The management of CRPS remains challenging for health care professionals. This review provides a summary of the recent literature on CRPS pathophysiology and management. The potential mechanisms of effective interventions are also discussed.