RANK-ligand and osteoprotegerin as biomarkers in the differentiation between periprosthetic joint infection and aseptic prosthesis loosening

Table 1 Patient demographics

Group	Total (n)	Mean age (± SD)	Sex (W:M)	Joint (hip:knee)
PJI	48	69.5 yr	27 female	22 TKA
		(± 12.1 yr)	21 male	26 THA
Aseptic loosening	51	68 yr	33 female	16 TKA
		(± 11.1 yr)	18 male	35 THA
Control	21	64.05 yr	13 female	13 TKA
		(± 11.9 yr)	8 male	8 THA
All	120	67.94	73 female	51 TKA
		(± 11.7)	47 male	69 THA
P		0.2686	0.8611	0.1110

One hundred and twenty consecutive patients were enrolled in the study prospectively. Group assignment was done according to the criteria as mentioned above. There was no statistical difference in patient age, gender, or distribution of joints in the groups. More women than men were enrolled in total and in all groups. There was a lower number of total hip arthroplasties (THA) than total knee arthroplasties (TKA) only in the control group. PJI: Periprosthetic joint infection.