Relationships among body weight, lipids and bone mass in elderly individuals with fractures: A case-control study

Table 1 Univariate and multivariate analysis of related factors for osteoporosis

	Univariate analysis				Multivariate analysis
	Normal (n = 85)	Osteopenia (n = 184)	Oeteoporosis (n = 251)	P value	OR	95%CI	P value
Age (year old)	75.54 ± 8.22	76.31 ± 8.00	79.72 ± 7.62	< 0.001	-0.04	0.016-0.064	0.001
Gender (n)				< 0.001	1.34	0.968-1.720	< 0.001
Male	48	81	49
Female	37	103	202
BMI (kg/m2)	25.46 ± 3.32	23.43 ± 3.32	21.83 ± 3.10	< 0.001	-0.018	-0.373	< 0.001
≤ 18.5 (n)	1 (1.18)	9 (4.89)	38 (15.14)	< 0.001
18.5-24 (n)	27 (31.76)	92 (50.00)	148 (58.96)
≥ 24 (n)	57 (67.06)	83 (45.11)	65 (25.90)
Ca (mmol/L)	2.21 ± 0.16	2.20 ± 0.15	2.22 ± 0.15	0.69
P (mmol/L)	1.05 ± 0.29	1.02 ± 0.19	1.04 ± 0.20	0.56
ALB (g/L)	38.21 ± 4.72	39.27 ± 4.26	38.49 ± 4.36	0.09
ALP (U/L)	64.02 ± 41.37	59.40 ± 38.83	70.89 ± 39.63	0.01	0.01	0.006-0.015	< 0.001
AST (U/L)	26.19 ± 14.73	27.64 ± 15.36	24.83 ± 16.01	0.19
ALT (U/L)	43.89 ± 30.07	48.50 ± 31.54	42.16 ± 31.87	0.11
TG (mmol/L)	1.62 ± 0.83	1.35 ± 0.87	1.09 ± 0.47	< 0.001	-0.56	-1.132	< 0.001
TC (mmol/L)	4.48 ± 1.15	4.27 ± 1.06	4.22 ± 1.01	0.16
HDL (mmol/L)	1.16 ± 0.31	1.21 ± 0.28	1.28 ± 0.44	0.1
LDL (mmol/L)	2.67 ± 0.93	2.48 ± 0.84	2.40 ± 0.80	0.12
CHD (n)	7	14	27	0.52

BMI: Body mass index; Ca: Calcium; P: Phosphorus; ALB: Albumin; ALP: Alkaline phosphatase; AST: Aspartate aminotransferase; ALT: Alanine transaminase; TG: Triglyceride; TC: Total cholesterol; HDL: High-density lipoprotein; LDL: Low-density lipoprotein; CHD: Coronary heart diseases.

Table 2 Male and female patients aged between 65 to 79 years old in related factors for osteoporosis

	Male (n = 106)	Female (n = 188)	P value
Age (year)	71.25 ± 4.39	72.18 ± 4.52	0.095
T-value	-1.51 ± 0.94	-2.5 ± 1.03	< 0.0001
BMI (kg/m2)	24.33 ± 3.52	23.63 ± 3.37	0.134
≤ 18.5 (n)	3 (2.83)	13 (6.91)	0.316
18.5-24(n)	48 (45.28)	85 (45.21)
≥ 24 (n)	55 (51.89)	90 (47.88)
Ca (mmol/L)	2.21 ± 0.13	2.25 ± 0.14	0.027
P (mmol/L)	1.00 ± 0.19	1.06 ± 0.14	0.01
ALB (g/L)	38.40 ± 4.11	39.67 ± 4.21	0.013
ALP (U/L)	69.29 ± 39.15	77.79 ± 35.53	0.032
AST (U/L)	26.86 ± 18.85	27.30 ± 19.34	0.258
ALT (U/L)	40.06 ± 27.97	38.94 ± 28.56	0.953
TG (mmol/L)	1.39 ± 0.73	1.45 ± 0.91	0.727
TC (mmol/L)	4.15 ± 0.95	4.52 ± 1.11	0.005
HDL (mmol/L)	1.13 ± 0.26	1.33 ± 0.45	< 0.001
LDL (mmol/L)	2.42 ± 0.83	2.68 ± 0.86	0.048

BMI: Body mass index; Ca: Calcium; P: Phosphorus; ALB: Albumin; ALP: Alkaline phosphatase; AST: Aspartate aminotransferase; ALT: Alanine transaminase; TG: Triglyceride; TC: Total cholesterol; HDL: High-density lipoprotein; LDL: Low-density lipoprotein.

Table 3 Male and female patients aged ≥ 80 years old in related factors for osteoporosis

	Male (n = 72)	Female (n = 154)	P value
Age (year)	85.60 ± 4.08	85.65 ± 33.89	0.839
T-value	-2.06 ± 1.21	-2.94 ± 1.29	< 0.0001
BMI (kg/m2)	22.34 ± 3.26	21.68 ± 3.12	0.15
≤ 18.5 (n)	10 (13.89)	22 (14.29)	0.829
18.5-24 (n)	41 (56.94)	93 (60.39)
≥ 24 (n)	21 (29.17)	39 (25.32)
Ca (mmol/L)	2.20 ± 0.17	2.21 ± 0.19	0.234
P (mmol/L)	1.01 ± 0.28	1.09 ± 0.58	0.092
ALB (g/L)	38.19 ± 4.34	38.04 ± 4.68	0.823
ALP (U/L)	56.21 ± 38.95	52.95 ± 40.44	0.455
AST (U/L)	23.61 ± 9.93	25.08 ± 10.77	0.238
ALT (U/L)	45.61 ± 28.78	54.45 ± 36.12	0.06
TG (mmol/L)	1.07 ± 0.44	1.08 ± 0.49	0.857
TC (mmol/L)	4.03 ± 0.99	4.20 ± 1.03	0.171
HDL (mmol/L)	1.17 ± 0.30	1.21 ± 0.32	0.425
LDL (mmol/L)	2.31 ± 0.78	2.29 ± 0.78	0.926

BMI: Body mass index; Ca: Calcium; P: Phosphorus; ALB: Albumin; ALP: Alkaline phosphatase; AST: Aspartate aminotransferase; ALT: Alanine transaminase; TG: Triglyceride; TC: Total cholesterol; HDL: High-density lipoprotein; LDL: Low-density lipoprotein.