Review
Copyright ©The Author(s) 2022.
World J Orthop. May 18, 2022; 13(5): 427-443
Published online May 18, 2022. doi: 10.5312/wjo.v13.i5.427
Table 1 Principal causes of pathological genu varum and genu valgum
Genu varum
Genu valgum
Idiopathic
Tibia vara (blount disease)
Infantile form
Adolescent form
Post-traumatic
Physeal bar
Malunion
Cozen’s phenomenon
Metabolic
Rickets
Renal disease
Local disorders
Infectious
Tumor or tumor-like lesion
Generalized disorders
Metabolic (e.g., rickets, renal osteodystrophy)
Constitutional disease of bone (i.e., bone dysplasia)
Juvenile arthritis
Neuromuscular
Table 2 Main differences between infantile and adolescent forms of Blount disease

Infantile form
Adolescent form
Age (yr)< 5> 10
Clinical features50% bilateral, overweight, lateral thrust during gait, possible internal rotation of the tibiaUsually unilateral, overweight/obese, male predominance
X-RAY appearanceVarus angulation at the epiphyseal-metaphyseal junction, metaphyseal beaking with apparent fragmentation, medial physeal line widening and irregularity; lateral tibial subluxation; possible compensatory distal femur valgusWidening of the proximal medial physeal line, normal shape of the proximal tibial metaphysis; possible presence of distal femur varus and compensatory distal tibial valgus
Natural historyDepending on the stage (spontaneous resolution is possible)Usually progressive without spontaneous resolution
Treatment optionsDepending on the stageSurgery only