Systematic Reviews
Copyright ©The Author(s) 2020.
World J Orthop. Jun 18, 2020; 11(6): 294-303
Published online Jun 18, 2020. doi: 10.5312/wjo.v11.i6.294
Table 1 Summary of studies characteristics
Ref.nTTOsMean age (yr)Males/ FemalesMean follow-up (mo)Outcome measures
Barrack et al[17], 19981515NRNR30 (24-48)ROM, KSS, Subjective satisfaction and function questionnaires
Bruni et al[19], 2013393972 ± 611/28144 ± 24ROM, VAS, KSS, Complications
Chalidis et al[2], 2009748760 (29-89)35/3949 (6-108)ROM, Complications
Choi et al[10], 2012 (1)365167 (38-87)20/1657 (7-126)ROM, KSS, Complications
Choi et al[11], 2012 (2)132660 (38-85)9/456 (15-126)ROM, KSS, Complications
Chun et al[18], 2019313173.8 ± 7.55/2662.4 (36-210)ROM, KSS, HSS, Complications
Hocking et al[1], 20075252NRNRNRROM, KSS, Complications
Le Moulec et al[12], 2014636372 ± 11.329/3627.8 ± 10.7ROM, IKS, Patellar height, Complications
Mendes et al[4], 2004646765.6 (35-93)25/3930 (5-60)ROM, KSS, Complications
Punwar et al[6], 2016384266 (33-92)24/146-24OKS, ROM, Walking status, Complications
Segur et al[13], 2014262673 (64-88)12/1440.8 (28.8- 3.2)KSS, WOMAC, ROM, Complications
Sun et al[3], 2014212170.1 ± 7.76/1548.1 ± 17.2ROM, KSS, HSS, Complications
Van den Broek et al[14], 2006373754.2 (37-78)NR28.4 (12-46)ROM, KSS, VAS for satisfaction, Complications
Vandeputte et al[16], 2017131353.6 (34-71)5/824ROM, KSS, Complications
Zonnenberg et al[15], 2014232369.6 (43-84)7/1616.1 (1-43)KSS, ROM, SF-36, Complications
Table 2 Surgery parameters
Ref.TTO length (cm)FixationApproachOscillating saw or osteotome
Barrack et al[17], 199810WiresMedial parapatellarSaw
Bruni et al[19], 20138-10WiresMedial parapatellarBoth
Chalidis et al[2], 200910.6 (7.9-15.3)Wires (n = 16)Medial parapatellarBoth
Screws (n = 9)
Wires and screws (n = 59)
Choi et al[10], 2012 (1)8Wires (n = 49)Medial parapatellarBoth
Screws (n = 2)
Choi et al[11], 2012 (2)8Wires (n = 25)Medial parapatellarBoth
Screws (n = 1)
Chun et al[18], 201910ScrewsMedial parapatellarBoth
Hocking et al[1], 20075-8WiresMedial parapatellarBoth
Le Moulec et al[12], 20147.7 ± 1.6WiresMedial parapatellarBoth
Mendes et al[4], 20048-10Wires (n = 66)Midvastus (n = 40)Saw
Wires and screw (n = 1)Medial parapatellar (n = 19)
Subvastus (n = 40)
Not noted (n = 4)
Punwar et al[6], 20167ScrewsMedial parapatellarBoth
Segur et al[13], 201410Wires (n = 25)Medial parapatellarSaw
Nonabsorbable sutures (n = 1)
Sun et al[3], 20146-8ScrewsMedial parapatellarSaw
van den Broek et al[14], 20066-8Screws (n = 36)Medial parapatellarBoth
Wires (n = 1)
Vandeputte et al[16], 20176-8Wires or screwsMedial parapatellarSaw
Zonnenberg et al[15], 20144-8Absorbable suturesMedial parapatellarOsteotome
Table 3 Tibial tubercle osteotomy-related complications
Ref.nNon-unionsTT fracturesProximal avulsion fracturesMetaphyseal tibial fracturesProximal migrationAnterior knee pain
Barrack et al[17], 199815-----3
Bruni et al[19], 201339-----11
Chalidis et al[2], 200974--3225
Choi et al[10], 2012 (1)36--215-
Choi et al[11], 2012 (2)13----3-
Chun et al[18], 201931------
Hocking et al[1], 200752-11-10-
Le Moulec et al[12], 2014634---4-
Mendes et al[4], 2004642--11311
Punwar et al[6], 201638---12-
Segur et al[13], 20142621----
Sun et al[3], 201421--2--5
van den Broek et al[14], 200637--1-23
Vandeputte et al[16], 201713------
Zonnenberg et al[15], 20142331----
Table 4 Mean range of motion, flexion, extension lag and flexion contracture values
Ref.nTotal ROM (°)
Flexion (°)
Extension lagFlexion contracture
PreopPostopPreopPostop
Barrack et al[17], 19981573811.5°
Bruni et al[19], 201339571135 cases < 15°
Chalidis et al[2], 200974609580952.5°2.5°
Choi et al[10], 2012 (1)364092
Choi et al[11], 2012 (2)1360946895
Chun et al[18], 201931101109109
Hocking et al[1], 200752913 cases
Le Moulec et al[12], 20146387.8103.715 cases10 cases
Mendes et al[4], 2004641011073 cases < 15°
Punwar et al[6], 201638859515 cases
Segur et al[13], 20142690951 case < 5°
Sun et al[3], 20142194.1101.73.8°
van den Broek et al[14], 20063781931 case
Vandeputte et al[16], 201713
Zonnenberg et al[15], 20142387.995.3
Table 5 Non-tibial tubercle osteotomy related complications
Ref.Complications
Barrack et al[17], 1998None reported
Bruni et al[19], 2013MUA for stiffness (n = 3)
Reinfections (n = 2)
DVT (n = 1)
Chalidis et al[2], 2009MUA for stiffness (n = 10)
Skin necrosis (n = 1)
Reinfections (n = 6)
Choi et al[10], 2012 (1)MUA for stiffness (n = 2)
Spacer subluxation (n = 1)
Reinfections (n = 10)
Choi et al[11], 2012 (2)MUA for stiffness (n = 2)
Spacer subluxation (n = 1)
Reinfections (n = 4)
Chun et al[18], 2019Skin necrosis (n = 2)
Hocking et al[1], 2007MUA for stiffness (n = 4)
Le Moulec et al[12], 2014None reported
Mendes et al[4], 2004MUA for stiffness (n = 9)
Pain not associated to TTO (n = 2)
Reinfection (n = 1)
Delayed wound healing (n = 5)
Transient peroneal nerve palsy (n = 3)
Punwar et al[6], 2016Reinfections (n = 2)
Segur et al[13], 2014Reinfections (n = 3)
Sun et al[3], 2014Reinfection (n=1)
van den Broek et al[14], 2006None reported
Vandeputte et al[16], 2017None reported
Zonnenberg et al[15], 2014MUA for stiffness (n = 1)
Fractures of tibial plateau (n = 5)
Patellar pain resolved with patellar resurfacing (n = 1)
Wound leakage resolved conservatively (n = 5)