T1ρ/T2 mapping and histopathology of degenerative cartilage in advanced knee osteoarthritis

Figure 1 T2 and T1ρ relaxation time measurement. T2 and T1ρ relaxation times were measured in a range of -10 to 20 degrees for the distal condyle and 70 to 100 degrees for the posterior condyle. The angle 0 is defined along B0.

Figure 2 Example of sagittal fat suppressed proton density-weighted imaging, T1ρ mapping and T2 mapping.

Figure 3 Example of normal thickness magnetic resonance imaging with corresponding hematoxylin and eosin, Alcian blue, and Masson trichrome stains. OA grade/stage/score in this case is 4/3/12, compatible with early OA. MRI: Magnetic resonance imaging; HE: Hematoxylin and eosin; OA: Osteoarthritis.