Chondroitin sulfate and glucosamine combination in patients with knee and hip osteoarthritis: A long-term observational study in Russia

Figure 1 Study design profile and recruitment of patients. Explanations for the participants excluded from the study were given in the Results section of this manuscript. GAH+CHS: 500 mg glucosamine hydrochloride and 400 mg chondroitin sulfate in one capsule; HOOS: Hip Disability and Osteoarthritis Outcome Score; KOOS: Knee Injury and Osteoarthritis Outcome Score; NSAID: Non-steroidal anti-inflammatory drugs.

Figure 2 Dynamics of Knee Injury and Osteoarthritis Outcome Score subscale scores. KOOS: Knee Injury and Osteoarthritis Outcome Score.

Figure 3 Dynamics of pain during the study (analysis of “Pain Frequency” questions in Knee Injury and Osteoarthritis Outcome Score and Hip Disability and Osteoarthritis Outcome Score). A: Knee osteoarthritis; B: Hip osteoarthritis. HOOS: Hip Disability and Osteoarthritis Outcome Score; KOOS: Knee Injury and Osteoarthritis Outcome Score.

Figure 4 Dynamics of Hip Disability and Osteoarthritis Outcome Score subscale scores. HOOS: Hip Disability and Osteoarthritis Outcome Score.

Figure 5 The need for concomitant symptomatic therapy with non-steroidal anti-inflammatory drugs for target joints at baseline and at the end of the observation period.