Diabetic foot: Which one comes first, the ulcer or the contracture?

doi:10.5312/wjo.v12.i2.61

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Feb 18, 2021 (publication date) through Nov 19, 2024

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World Journal of Orthopedics

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2218-5836

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Orthop. Feb 18, 2021; 12(2): 61-68
Published online Feb 18, 2021. doi: 10.5312/wjo.v12.i2.61

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Figure 1 Schematic diagram indicating how a vicious cycle can occur between equinus contracture and foot ulceration in patients with diabetes. TGF-β: Transforming growth factor β; AGEs: Advanced glycation end-products; RAAS: Renin angiotensin aldosterone system; ECM: Extracellular matrix.

Citation: Primadhi RA, Herman H. Diabetic foot: Which one comes first, the ulcer or the contracture? World J Orthop 2021; 12(2): 61-68
URL: https://www.wjgnet.com/2218-5836/full/v12/i2/61.htm
DOI: https://dx.doi.org/10.5312/wjo.v12.i2.61