Charcot-Marie-Tooth hereditary neuropathy revealed after administration of docetaxel in advanced breast cancer

Table 1 Summary of all the reported cases in the literature of Charcot-Marie-Tooth revealed after administration of chemotherapy

Ref.	Patient characteristics	Drug	Malignancy	Signs and symptoms	Diagnosis
Uno et al[7], 1999	44 M	Vincristine	NHL	Rapid and marked weakening progressing to quadriplegia and bulbar palsy pes cavus (hollow foot)	Slower nerve conduction velocity 17p11.2-12 duplication
Martino et al[4], 2005	F	Paclitaxel/ Carboplatine	Ovarian cancer	Distal sensory and motor neuropathy; Unable to walk, write, or drive	Already diagnosed
Hildebrandt et al[8], 2000	52 F	Vincristine	NHL	Dysphagia, dysarthria, muscular weakness of both lower and upper extremities, areflexia, paraesthesia of the fingertips and bilateral sensory impairment of feet and lower legs	Peripheral axonal and demyelinating sensorimotor neuropathy 17p11.2 duplication
Graf et al[5], 1996	9 F	Vincristine	Acute lymphoblastic leukemia	Severe acquired weakness, areflexia and distal muscle atrophy	17p duplication
	18 F		Burkitt lymphoma	Pes cavus, distal muscle atrophy and weakness, stocking glove sensory deficits	17p duplication Slower nerve conducting velocity
	46 M		Testicular embryonal cell carcinoma	Foot drop, per cavus and areflexia, marked weakness	Slow motor nerve conduction velocity

NHL: Non-Hodgkin lymphoma; M: Male; F: Female.