Fluoxetine induces cytotoxic endoplasmic reticulum stress and autophagy in triple negative breast cancer

Table 1 Proportion of cells in each cycle phase in the absence and presence of fluoxetine

	SUM149PT Control	SUM149PT 10 μmol/L FLX	Late MCF10A Control	Late MCF10A 10 μmol/L FLX	T47D Control	T47D 10 μmol/L FLX
24 h
Sub G	1.1	1.72	0.66	1.772	1.86	1.63
	(0.34)1	(0.55)	(0.13)	(0.2)	(0.26)	(0.18)
G1	39.6	62.412	60.26	79.892	56.03	59.21
	(0.74)	(1.02)	(1.59)	(0.71)	(2.05)	(0.55)
S	34.64	20.182	23.78	10.752	21.14	18.26
	(1.28)	(1.11)	(1.16)	(0.43)	(1.12)	(1.45)
G2/M	25.26	16.122	15.8	7.862	21.44	21.39
	(0.79)	(0.3)	(0.65)	(0.13)	(0.98)	(1.32)
48 h
Sub G	1.91	6.67	0.41	10.263	1.7	2.66
	(0.42)	(2.47)	(0.05)	(0.52)	(0.32)	(0.39)
G1	46.79	67.733	65.48	79.773	57.52	62.35
	(1.94)	(1.16)	(0.93)	(1.3)	(2.01)	(1.31)
S	29.69	14.012	22.24	6.593	22.33	18.07
	(2.79)	(0.84)	(0.6)	(0.72)	(1.54)	(1.19)
G2/M	22.24	11.902	12.31	3.583	18.95	17.32
	(1.08)	(2.64)	(0.43)	(0.13)	(0.24)	(0.29)

¹Numbers in parentheses represent standard errors;

²P-value < 0.05 compared to matching control;

³P-value < 0.001 compared to matching control; FLX: Fluoxetine.