MicroRNAs in cancer therapeutic response: Friend and foe

Table 1 miRNAs involved in chemotherapy response regulation in breast cancer

miRNA	Drug	Target(s)	Ref.
miR-328	Mitoxantrone	BRCP/ABCG2	[75]
miR-21	Doxorubicin	MDR1, PDCD4	[81]
miR-451	Doxorubicin	MDR1	[76]
miR-130/107	Cisplatin	RAD51D	[125]
miR-345	Cisplatin	MDR1	[77]
miR-326	VP16/Doxorubicin	MRP1	[78]
miR-128	Doxorubicin	BMI1, ABCC5	[79]
miR-34a	Docetaxel	BCL-2, CCND1	[83]
miR-125b	Doxorubicin	BAK1	[84]
	Paclitaxel	E2F3	[85]
miR-200b/c	Doxorubicin	ZEB1, PTEN	[86,87]

Table 2 miRNAs involved in antiendocrine therapy response in breast cancer

miRNA	Drug	Target(s)	Ref.
miR-221/222	Tamoxifen	P27Kip1	[91]
		ERα
	Fulvestrant	TGF-β	[93]
miR-181b	Tamoxifen	TIMP3	[94]
miR-30c	Tamoxifen		[96,97]
miR-342	Tamoxifen	cyclin B1	[126]
miR-451	Tamoxifen	14-3-3ζ	[127]
Let-7	Tamoxifen	ER-α36	[128]
miR-128a	Letrozole	TGFαR1	[129]