Correlation between gut microbiota and tumor immune microenvironment: A bibliometric and visualized study

Table 1 Top 10 countries/regions with the highest number of research publications

No.	Country	Np, n	Np (%)	Nc, n	Centrality
1	China	226	46	95	0.12
2	United States	152	31	119	0.68
3	Italy	33	6.7	51	0.26
4	Japan	25	5.1	1064	0.07
5	France	18	3.7	499	0.04
6	Germany	16	3.3	1414	0.1
7	Canada	16	3.3	714	0.06
8	Australia	13	2.6	885	0.16
9	India	12	2.4	81	0.13
10	England	11	2.2	45	0.21

Np: Number of publications; Nc: Number of citations.

Table 2 Top 10 institutions with the highest number of publications

No.	Institution	Country	Np, n	Np (%)	Nc, n	Centrality
1	Shanghai Jiao Tong University	China	15	3.1	734	0.05
2	Zhejiang University	China	15	3.1	355	0.03
3	UTMD Anderson Cancer Center	United States	12	2.4	1292	0
4	Harvard School of Dental Medicine	United States	12	2.4	680	0.02
5	NIH National Cancer Institute	United States	12	2.4	1782	0.12
6	Fudan University	China	11	2.2	376	0.04
7	Huazhong University of Science & Technology	China	10	2	1112	0
8	Sun Yat-Sen University	China	9	1.8	237	0
9	Pennsylvania Commonwealth System of Higher Education	United States	9	1.8	1065	0
10	Sichuan University	China	8	1.6	52	0.08

Np: Number of publications; Nc: Number of citations.

Table 3 Top 10 authors with the highest influence based on the H-Index

Author	H_index	G_index	M_index	Articles	Citations
Trinchieri G	7	8	0.636	8	1213
Li J	6	8	0.667	8	652
Liu Z	6	9	1.000	9	156
Zitvogel L	6	6	0.545	6	420
Garrett WS	5	5	0.455	5	1437
Liu Y	5	10	1.000	10	135
Wang S	5	5	0.625	5	114
Wang Y	5	10	0.833	10	116
Wargo JA	5	7	0.556	7	1160
Zhang Y	5	8	1.000	8	188

Table 4 Top 5 co-cited authors based on frequency

Authors	Degree	Centrality	Sigma	Frequency
Fan XZ	14	0.21	1.00	125
Pushalkar S	19	0.37	1.00	105
Michaud DS	12	0.11	1.51	92
Farrell JJ	12	0.12	1.00	84
Kostic AD	15	0.16	1.00	78

Table 5 Top 10 journals and co-cited journals with the most publications

No.	Journal	Np, n	IF in 2024	JCR	Cocited journal	Cocitations	IF in 2024	JCR
1	Frontiers in Immunology	40	5.7	Q1	Science	2484	44.7	Q1
2	Cancers	37	5.2	Q2	Nature	1753	50.5	Q1
3	Frontiers in Oncology	18	3.5	Q2	Cell	1297	45.5	Q1
4	International Journal of Molecular Sciences	17	4.9	Q1	Cancer Research	953	12.5	Q1
5	Frontiers in Microbiology	10	4	Q2	Plos one	840	2.9	Q1
6	Biochimica Et Biophysica Acta-Reviews on Cancer	8	9.7	Q1	Nature Communications	839	14.7	Q1
7	Cancer Letters	8	9.1	Q1	Frontiers in Immunology	826	5.7	Q1
8	Frontiers in Cellular and Infection Microbiology	8	4.6	Q1	Gastroenterology	764	25.7	Q1
9	Gut Microbes	7	12.2	Q1	Gut	764	23	Q1
10	Seminars in Cancer Biology	7	12.1	Q1	Nature Medicine	710	58.7	Q1

IF: Impact factor; JCR: Journal Citation Reports; Np: Number of publications.

Table 6 Top 10 co-cited references referring to cocitations

Ref.	Year	Journal	Cocitations	Centrality
Fan et al[18]	2018	Gut	100	0.52
Flemer et al[19]	2018	Gut	47	0.23
Karpiński et al[20]	2019	Microorganisms	44	0.17
Nejman et al[21]	2020	Science	39	0.29
Pushalkar et al[22]	2018	Cancer Discov	39	0.13
Yang et al[23]	2018	Front Microbiol	37	0.22
Zhang et al[24]	2020	Front Cell Infect Mi	36	0.08
Brennan et al[25]	2019	Nat Rev Microbiol	36	0.23
Peters et al[26]	2017	Cancer Res	36	0.09
Lamont et al[27]	2018	Nat Rev Microbiol	36	0.08

Table 7 Top 10 keywords based on their occurrences

No.	Keyword	Occurrences	Centrality	Year
1	Gut microbiota	223	0.06	2018
2	Tumor microenvironment	173	0.01	2022
3	Immunotherapy	121	0.00	2022
4	Cancer	109	0.10	2015
5	Colorectal cancer	91	0.13	2015
6	Microbiome	77	0.02	2021
7	Gut microbiome	74	0.04	2021
8	Inflammation	74	0.09	2018
9	Fusobacterium-nucleatum	68	0.07	2016
10	Cells	62	0.05	2019