5-mRNA-based prognostic signature of survival in lung adenocarcinoma

Table 1 Data and studies involved several prediction models for the prognostic signature of non-small cell lung cancer/ lung adenocarcinoma

Datasets	Model-related genes	Application	Ref.
GEO (GSE19188, GSE33532)	DLGAP5, KIF11, RAD51AP1, CCNB1, AURKA, CDC6, OIP5, NCAPG	Prognostic signature for predicting overall survival in lung adenocarcinoma	Li et al[3], 2018
GEO (GSE31210, GSE37745, GSE50081) + TCGA	PLEKHH2, ISCU, CLUL1, CHRDL1, PAIP2B, CDCP1	Prognostic signature for predicting both disease-free and overall survival in non-small cell lung cancer	Zuo et al[4], 2019
GEO (GSE31210, GSE37745, GSE50081) + TCGA	CDCP1, HMMR, TPX2, CIRBP, HLF, KBTBD7, SEC24B-AS1, SH2B1	Prognostic Signature for predicting overall survival of early-stage non-small cell lung cancer	He et al[5], 2019
TCGA	RHOV, CD109, LINC00941, FRRS1	Prognostic signature for predicting overall survival in lung adenocarcinoma	Shukla et al[6], 2016
GEO (GSE3141, GSE30219, GSE50081) + TCGA	ADAM12, BTK, ERG	Prognostic gene signature associated with the microenvironment of lung adenocarcinoma	Yue et al[7], 2019
GEO (GSE50081, GSE30219, GSE31210, GSE19188, GSE37745, GSE3141, GSE31908)	ABCC4, ADRBK2, KLHL23, PDS5A, UHRF1, ZNF551	Prognostic signature for predicting overall survival in non-small cell lung cancer	Huang et al[8], 2016
GEO (GSE50081, GSE31210, GSE30219, GSE29013, GSE68465, GSE42127) + E-MTAB-923	STAT1, CLU, GTSE1, NUSAP1, ABCA8, TNNT1, ENTPD3, CPA3	Prognostic signature for predicting overall survival in non-small cell lung cancer	Shahid et al[9], 2016
GEO (GSE8894, GSE14814, GSE30219, GSE31210, GSE37745, GSE50081)	KIF15, DLGAP5, ASPM, ADAM10, RAD51AP1, FGFR10P, NCGAP	Prognostic gene expression signature for early stage lung adenocarcinoma	Krzystanek et al[10], 2016
TCGA	BCHE, CCNA1, CYP24A1, DEPTOR, MASP2, MGLL, MYO1A, PODXL2, RAPGEF3, SGK2, TNNI2, ZBTB16	Prognostic signature for predicting overall survival in lung adenocarcinoma	Zengin et al[11], 2020
TCGA	PTPRH, OGFRP1, LDHA, AL365203.1, LINC02178, AL512488.1, LINC01312, AL353746.1, DRAXINP1, LINC02310	Prognostic signature for predicting overall survival in lung adenocarcinoma	Li et al[12], 2018
14 GEO datasets	ABCC4, ADRBK2, KLHL23, PDS5A, UHRF1, ZNF551	Prognostic signature for predicting overall survival in non-small cell lung cancer	Xie et al[13], 2019
GEO (GSE31210, GSE32863, GSE40791, GSE43458, GSE75037) + TCGA	AURKA, CDC20, TPX2	Prognostic signature for predicting overall survival in smoking-related lung adenocarcinoma	Zhang et al[14], 2019

GEO: the Gene Expression Omnibus; TCGA: the Cancer Genome Atlas.