Copyright
©The Author(s) 2021.
World J Clin Oncol. Jul 24, 2021; 12(7): 507-521
Published online Jul 24, 2021. doi: 10.5306/wjco.v12.i7.507
Published online Jul 24, 2021. doi: 10.5306/wjco.v12.i7.507
Location | Classification | Gene symbol | Eponym | Predominant GAG | Studied in ESCC | Ref. |
Intracellular | Secretory granules | SRGN | Serglycin | Heparin/CS | Serglycin | Zhu et al[57] |
Cell-surface | Transmembrane | SDC | Syndecan 1-4 | HS/CS | Syndecan-1, -2 | Mikami et al[58], Szumilo et al[60] and Huang et al[61] |
CSPG4 | NG2 | CS/DS | ||||
TGFBR3 | Betaglycan | HS/CS | ||||
PTPRZ1 | Phosphacan | CS/DS | ||||
GPI-anchored | GPC | Glypican 1-6 | HS | Glypican-1, -3 | Hara et al[62], Li et al[63], Harada et al[64] and Song[65] | |
Pericellular | Basement membrane zone | HSPG2 | Perlecan | HS/CS | ||
AGRN | Agrin | HS | ||||
COL18A1 | Collagen XVIII | HS | Endostatin | Zheng et al[71], Zhong et al[72] and Chen et al[73] | ||
COL15A1 | Collagen XV | CS/HS | ||||
Extracellular | Hyalectans | ACAN | Aggrecan | CS/KS | ||
VCAN | Versican | CS/DS | ||||
NCAN | Neurocan | CS/DS | ||||
BCAN | Brevican | CS/DS | ||||
SLRPs, Canonical Class I | DCN | Decorin | CS/DS | Decorin | Wu et al[83], Ji et al[84] and Augoff et al[85] | |
BGN | Biglycan | CS/DS | Biglycan | Zhu et al[97] | ||
ASPN | Asporin | |||||
ECM2 | ECM2 | |||||
ECMX | ECMX | |||||
SLRPs, Canonical Class II | FMOD | Fibromodulin | KS | |||
LUM | Lumican | KS | Lumican | Kashyap et al[102,103] | ||
PRELP | PRELP | |||||
KERA | Keratocan | KS | ||||
OMD | Osteoadherin | KS | ||||
SLRPs, Canonical Class III | EPYC | Epiphycan | CS/DS | |||
OPTC | Opticin | |||||
OGN | Osteoglycin | |||||
SLRPs, Non-Canonical Class IV | CHAD | Chondroadherin | ||||
NYX | Nyctalopin | |||||
TSKU | Tsukushi | |||||
SLRPs, Non-Canonical Class V | PODN | Podocan | ||||
PODNL1 | Podocan-Like 1 | |||||
SPOCK | SPOCK | Testican 1-3 | HS | Testican-1 | Song et al[108] |
- Citation: Zhu Y, Cheung ALM. Proteoglycans and their functions in esophageal squamous cell carcinoma. World J Clin Oncol 2021; 12(7): 507-521
- URL: https://www.wjgnet.com/2218-4333/full/v12/i7/507.htm
- DOI: https://dx.doi.org/10.5306/wjco.v12.i7.507