Circulating cytokeratin-positive cells and tumor budding in colorectal cancer

Figure 1 This image illustrates the blood draw from the mesenteric vein. A standard i.v. catheter is used to cannulate the mesenteric vein after removal of the clip.

Figure 2 Cytokeratin 18 (Clone cytokeratin 2) cytochemistry. A: A single CK⁺ cell is shown in this image; B: A CK⁺ cell cluster is shown in this image. CK⁺: Cytokeratin-positive.

Figure 3 Cancer specific survival. A: Circulating CK⁺ cell negative vs positive; B: Circulating CK⁺ cell cluster negative vs positive; C: Tumor budding negative/low grade vs high grade. CK⁺: Cytokeratin-positive.