Behavior of advanced gastrointestinal stromal tumor in a patient with von-Recklinghausen disease: Case report

Figure 1 Cafe’-au-lait pigmentation with multiple cutaneous and subcutaneous nodules on the trunk.

Figure 2 Results of image. A: Computed tomography scan: oral and IV contrast revealed a large thick wall cavity mass (17 cm × 11 cm) with the enhancing wall; B: Barium follow-through delineated a large cavity connected to a segment of small bowel located at the mid-pelvic region; C: Magnetic resonance imaging of T1 and T2 coronal image shows a large cavity lesion containing gas and fluids and connected to a segment of small bowel but not related to the ovaries.

Figure 3 Congested exophytic mass measuring approximately 17 cm × 11 cm × 7 cm from the jejunal wall.

Figure 4 Histopathological examination. A: Invasive tumor comprising of spindle shaped cells arranged in bundles and fascicles; B: Many bizarre nuclei (oval to elongated hyperchromatic nuclei) and multinucleated tumor giant cells; C: Immunohistochemistry staining was positive for CD117.