LOH-profiling by SNP-mapping in a case of multifocal head and neck cancer

Figure 1 Overview of the locations with biopsy-proven squamous cell carcinoma and squamous cell carcinoma in situ in the upper aerodigestive tract of the patient (profile of the hypopharynx, larynx and trachea and top view of the tongue, hypopharynx and larynx). L: Left; R: Right; SSC: Squamous cell carcinoma; SSCis: Squamous cell carcinoma in situ.

Figure 2 Single nucleotide polymorphism 50K Xbal genome-wide loss of heterozygosity profiling using the AffymetrixGeneChip Assay System. Regions of genomic deletions between 1.6 Mb and 8.1 Mb in size were identified on 5 chromosomes (red labeling). The x-axis shows physical position along the respective chromosome. The y-axis indicates -log10P values where homozygous stretches are due to loss of heterozygosity.