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©2011 Baishideng Publishing Group Co.
World J Clin Oncol. Mar 10, 2011; 2(3): 135-149
Published online Mar 10, 2011. doi: 10.5306/wjco.v2.i3.135
Published online Mar 10, 2011. doi: 10.5306/wjco.v2.i3.135
Figure 1 Schematic representation of the epidermal growth factor receptor pathway.
EGFR: Epidermal growth factor receptor; mAB: Monoclonal antibody; TKI: Tyrosine kinase inhibitor; mTOR: Mammalian target of rapamycin; PI3K: Phosphoinositide 3-kinases; MEK: MAP kinase or ERK kinase.
Figure 2 Schematic representation of the vascular endothelial growth factor pathway.
VEGF: Vascular endothelial growth factor; PlGF: Placental growth factor; mAb: Monocolonal antibody; VEGFR: Vascular endothelial growth factor receptor; mTOR: Mammalian target of rapamycin; PI3K: Phosphoinositide 3-kinases; MEK: MAP kinase or ERK kinase; TKI: Tyrosine kinase inhibitor.
Figure 3 Schematic representation of the hedgehog pathway.
Hh: Hedgehog; Ptch: Patched; Smo: Smoothened; Sufu: Fused and suppressor of fused.
- Citation: Spratlin JL, Chu Q, Koski S, King K, Mulder K. Targeting metastatic upper gastrointestinal adenocarcinomas. World J Clin Oncol 2011; 2(3): 135-149
- URL: https://www.wjgnet.com/2218-4333/full/v2/i3/135.htm
- DOI: https://dx.doi.org/10.5306/wjco.v2.i3.135