New cheaper human papilloma virus mass screening strategy reduces cervical cancer incidence in Changsha city: A clinical trial

Figure 1 Changsha human papillomavirus cervical cancer prevention screening flow chart. Cervical cancer screening included gynecological examination, vaginal secretion examination, and high-risk human papillomavirus (HPV) type testing. Cervical cytology examination (ThinPrep cytology test) was performed in women who were positive for HPV types other than 16 and 18. Vaginal colposcopy was performed in women who were positive for HPV 16 and 18, as well as those who were positive for ThinPrep cytology test. If the results of vaginal colposcopy examination were abnormal, histopathological examination was performed. HPV: Human papillomavirus.

Figure 2 Characteristics of human papillomavirus infection in Changsha city. A: The stacked bar charts show the incidence of infection at different ages. The abscissa indicates the age, the left ordinate indicates the number of people in the bar, and the right ordinate indicates the infection rate of the line; B: The percentage bar chart shows infection at different ages; C: The stacked bar charts show the incidence of cancer at different ages. The data were calculated and sorted by Excel. CIN: Cervical intraepithelial neoplasia.

Figure 3 Infection rate and multiple infection with various human papillomaviruses in Changsha city. A: The stacked bar charts show infection with different subtypes; B: The percentage bar chart shows infection with different subtypes. HPV: Human papillomavirus.

Figure 4 Statistical analysis of the relationship between human papillomavirus and cervical lesions in Changsha city. A: The stacked bar charts show the carcinogenesis with different subtypes of human papillomavirus; B: The percentage bar chart shows carcinogenesis with different subtypes. AIS: Adenocarcinoma in situ; HPV: Human papillomavirus; CIN: Cervical intraepithelial neoplasia.

Figure 5 Cervical lesion distribution in the first and second rounds of screening, and statistical analysis of human papillomavirus 16/18 features. A: The stacked bar charts show the carcinogenesis in the first screening; B: The stacked bar charts show the carcinogenesis in the second screening; C: The stacked bar charts compare the carcinogenesis of the human papillomavirus 16/18-positive women in the two-screening population. AIS: Adenocarcinoma in situ; HPV: Human papillomavirus; CIN: Cervical intraepithelial neoplasia.