Meta-Analysis
Copyright ©The Author(s) 2023.
World J Clin Oncol. Nov 24, 2023; 14(11): 504-517
Published online Nov 24, 2023. doi: 10.5306/wjco.v14.i11.504
Figure 1
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Figure 1 Flow diagram for searching and filtering eligible studies included in the meta-analysis.
Figure 2
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Figure 2 Forest plots of the five studies show a shorter overall survival and disease-free survival/progression-free survival/recurrence-free survival in early pancreatic patients with positive pre-treatment or post-treatment circulating tumor cells detection. A: Overall survival; B: Disease-free survival/progression-free survival/recurrence-free survival. CI: Confidence interval.
Figure 3
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Figure 3 Forest plot of the three studies that used the CellSearch system shows a decreased disease-free survival/progression-free survival/recurrence-free survival in early pancreatic patients that were positive pre-treatment or post-treatment for circulating tumor cells. CI: Confidence interval.
Figure 4
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Figure 4 Sensitivity analysis of the influence of each study on the pooled results for the overall survival and disease-free survival/progression-free survival/recurrence-free survival subgroups. A: Overall survival; B: Disease-free survival/progression-free survival/recurrence-free survival.
Figure 5
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Figure 5 Funnel plots were generated for the included studies to determine whether or not publication bias was found for both the overall survival and disease-free survival/progression-free survival/recurrence-free survival subgroups. A: Overall survival; B: Disease-free survival/progression-free survival/recurrence-free survival.
Figure 6
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Figure 6 Forest plots of the four studies show that the carbohydrate antigen 19-9 level in the venous blood of early-stage pancreatic cancer patients was not an independent predictor of a shorter time to recurrence. CI: Confidence interval.
Figure 7
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Figure 7 Forest plots of the three studies, that detected the carbohydrate antigen 19-9 level in the venous blood before surgery, show that it was not an independent predictor of a shorter time to recurrence for early-stage pancreatic cancer patients. CI: Confidence interval.