Review
Copyright ©The Author(s) 2021.
World J Clin Oncol. Oct 24, 2021; 12(10): 845-867
Published online Oct 24, 2021. doi: 10.5306/wjco.v12.i10.845
Figure 1
Figure 1 Interleukin-6, interleukin-23 e transforming growth factor-β stimuli for interleukin-17A production and the role of Prostalglandins E2 in Th17 cells transdifferentiation into interleukin-17NEG FOXP3 cell. TGF: Transforming growth factor; IL: Interleukin; PGE2: Prostalglandins E2.
Figure 2
Figure 2 Main protumor mechanisms related to the Th17 immune response profile. STAT3: Signal transducer and activator of transcription 3; MMP2: Matrix metalloproteinases 2; VEGF: Vascular endothelial growth factor; PD-L1: Programmed death-ligand 1; PGE1: Prostalglandins E1; PGE2: Prostalglandins E2; TIM-3: T-cell immunoglobulin-3; NF-κB: Nuclear factor kappa-light-chain-enhancer of activated B cells; AP-1: Activating protein-1.