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©2011 Baishideng Publishing Group Co., Limited. All rights reserved.
World J Clin Oncol. Nov 10, 2011; 2(11): 367-376
Published online Nov 10, 2011. doi: 10.5306/wjco.v2.i11.367
Published online Nov 10, 2011. doi: 10.5306/wjco.v2.i11.367
Epidermal growth factor receptor and K-Ras in non-small cell lung cancer-molecular pathways involved and targeted therapies
Ramon Andrade de Mello, Dânia Sofia Marques, Department of Medical Oncology, Portuguese Oncology Institute, Porto 4200-072, Portugal
Ramon Andrade de Mello, 2nd Department of Medicine, Discipline of Clinical Semiotics, Faculty of Medicine, University of Porto, Porto 4200-319, Portugal
Rui Medeiros, Molecular Oncology Unit CI, IPOPFG, Porto 4200-072, Portugal
Rui Medeiros, 2nd Departament of Molecular Immunology and Pathology, Instituto de Ciências Biomédicas Abel Salazar (ICBAS), University of Porto, Porto 4099-003, Portugal
António MF Araújo, Head of Lung Clinic of the Department of Medical Oncology, Portuguese Oncology Institute, Porto 4200-072, Portugal
Author contributions: All authors contributed equally to manuscript preparation.
Supported by Portuguese Oncology Institute – Research Center
Correspondence to: Ramon Andrade de Mello, MD, Department of Medical Oncology, Portuguese Oncology Institute, Rua Dr António Bernadino de Almeida, S./N., Porto 4200-072, Portugal. ramonmello@med.up.pt
Telephone: +351-22-508-4000 Fax: +351-22-508-4010
Received: June 8, 2011
Revised: October 10, 2011
Accepted: October 17, 2011
Published online: November 10, 2011
Revised: October 10, 2011
Accepted: October 17, 2011
Published online: November 10, 2011
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