Efficacy of small-volume simethicone given at least 30 min before gastroscopy

Table 1 Baseline characteristics of the patients n (%)

	Placebo group(n = 27)	Simethicone group(n = 27)	P vaule
Mean age (yr ± SD)	52.9 ± 15.5	57.7 ± 12.5	0.215
Male gender (%)	9 (33.3)	15 (55.6)	0.1
Mean premedication time (min:s ± SD)	41:08 ± 9:56	44:46 ± 12:36	0.245
Indication for gastroscopy
Dyspepsia	19 (70.4)	10 (37.0)	0.014
Reflux symptoms	3 (11.1)	6 (22.2)	0.467
Positive H. pylori serology	0	1 (3.7)	1
Variceal screen	1 (3.7)	2 (7.4)	1
Anemia	4 (14.8)	3 (11.1)	1
Dysphagia	0	1 (3.7)	1
Intestinal metaplasia surveillance	0	3 (11.1)	0.236
Cancer surveillance after endoscopic mucosal resection	0	1	1

H. pylori: Helicobacter pylori.

Table 2 Study results

	Placebo group	Simethicone group	P value
TMVS ± SD	8.89 ± 1.97	5.78 ± 1.65	< 0.001
Mean esophagus score ± SD	1.59 ± 0.57	1.48 ± 0.57	0.482
Mean duodenum score ± SD	2.26 ± 0.81	1.26 ± 0.53	< 0.001
Mean antrum and angularis score ± SD	2.56 ± 1.05	1.30 ± 0.54	< 0.001
Mean body and fundus score ± SD	2.44 ± 0.97	1.74 ± 0.81	0.006
Mean volume of additional water flushes required ± SD (mL)	84.81 ± 110.18	3.89 ± 11.46	< 0.001
Procedure time ± SD (s)	193.67 ± 87.04	154.85 ± 49.07	0.049

TMVS: Total mucosal visibility score.