Review
Copyright ©2014 Baishideng Publishing Group Co.
World J Gastrointest Pharmacol Ther. May 6, 2014; 5(2): 63-76
Published online May 6, 2014. doi: 10.4292/wjgpt.v5.i2.63
Table 1 Reported incidence of thiopurine adverse drug effects
ADEIncidence
GI symptoms[155]8%
Hepatotoxicity[179,180]3%-15%
NRH[51]0.6%-1.28%
Pancreatitis[155]4%
Leucopenia[180]2%-15%
Myelotoxicity[155]4%
Lymphoma[155]0.1%
Infections[180]0.3%-7.4%
Intolerance[57,155]17%
ADE: Adverse drug effects; GI: Gastrointestinal; NRH: Nodular regenerative hyperplasia.