Typical and atypical symptoms of gastro esophageal reflux disease: Does Helicobacter pylori infection matter?

Figure 1 Distribution of symptoms in Helicobacter pylori-positive (on the left) and Helicobacter pylori-negative (on the right) patients. The data represent the percentage distribution of typical symptoms (in dark grey) and atypical extraesophageal symptoms (in light grey). H. pylori: Helicobacter pylori.

Figure 2 Distribution of symptoms in patients who eradicated Helicobacter pylori less than 6 mo before pH monitoring (on the left) and in patients who eradicated Helicobacter pylori more than 6 mo earlier (on the right). The data represent the percentage distribution of typical symptoms (in dark grey) and atypical extraesophageal symptoms (in light grey). H. pylori: Helicobacter pylori.

Figure 3 Percentage distribution of typical (dark grey) and atypical (light grey) symptoms in our four different groups of patients. From left to right, the bars indicate the group of patients Helicobacter pylori (H. pylori)-positive (P), eradicated less than 6 mo before pH monitoring (RE), eradicated more than 6 mo earlier (E), and H. pylori-negative (N). As shown, there is a progressive change in the percentage of symptoms related to the pattern of H. pylori infection. ^dP < 0.001 between N and P; ^bP < 0.01 between N and RE; ^aP < 0.05 between E and P.