Capsaicin-sensitive afferentation represents an indifferent defensive pathway from eradication in patients with H. pylori gastritis

Figure 1 Immune-staining for transient receptor potential vanilloid 1 (A), calcitonin gene-related peptide (B) and substance P (C) in the gastric mucosa of patients with Helicobacter pylori positive chronic gastritis (× 100). A: The arrows show the cytoplasmic immunosignals; B: The arrows show the immunosignals of calcitonin gene-related peptide; C: The granular small spot-like signals of substance P along the mucosal blood vessels are indicated by arrows.

Figure 2 Changes in the presence of transient receptor potential vanilloid 1, calcitonin gene-related peptide and substance P in the gastric mucosa of patients with Helicobacter pylori positive chronic gastritis before and after eradication therapy obtained by immnohistochemistry. TRVP1: Transient receptor potential vanilloid 1; CGRP: Calcitonin gene-related peptide; SP: Substance P; NS: Not significant. ^bP < 0.01.