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©2012 Baishideng Publishing Group Co.
World J Gastrointest Pathophysiol. Apr 15, 2012; 3(2): 51-59
Published online Apr 15, 2012. doi: 10.4291/wjgp.v3.i2.51
Published online Apr 15, 2012. doi: 10.4291/wjgp.v3.i2.51
Table 1 The differences in the histopathological diagnosis of colorectal intraepithelial tumors between Japan and Western countries
Intramucosal epithelial tumor | |||
Japan | Low grade adenoma | High grade adenoma | Intramucosal adenocarcinoma |
United Kingdom | Mild dysplasia | Moderate dysplasia | Severe dysplasia |
United States | Low grade dysplasia | High grade dysplasia |
Table 2 The rates of en bloc resection and local recurrence of tumors larger than 20 mm in diameter treated by endoscopic mucosal resection
Table 3 The rates of en bloc resection and complete resection by endoscopic submucosal dissection
Author | No. of cases | Rate of en bloc resection (%) | Perforation rate (%) | Post-operative bleeding rate (%) |
Saito et al[7] | 1111 | 88.0 | 4.9 | 1.5 |
Toyonaga et al[32] | 468 | 98.9 | 1.5 | 1.5 |
Isomoto et al[33] | 292 | 90.1 | 8.2 | 0.7 |
Yoshida et al[34] | 250 | 86.8 | 6.0 | 2.4 |
Fujishiro et al[35] | 200 | 91.5 | 10.4 | 1.0 |
Zhou et al[36] | 74 | 93.2 | 8.1 | 1.3 |
Tanaka et al[37] | 70 | 80.0 | 10.0 | 1.4 |
Our recent data | 410 | 92.6 | 4.1 | 1.9 |
Table 4 Characteristics of colorectal tumors resected by endoscopic submucosal dissection
SM | M | A | Pvalue | |
Number of tumors | 33 | 144 | 157 | |
Median age (yr) (range) | 65.5 (46-83) | 67.9 (48-87) | 67.5 (39-87) | |
Male/female | 21/12 | 86/58 | 81/76 | NS |
Tumor size (mm) (range) | 26.5 (10-60) | 35.1 (10-130) | 27.0 (10-80) | P < 0.01 |
Location (colon/ rectum) | 18:15 | 87:57 | 124:33 | P < 0.01 SM:A |
Morphology (protruding/ superficial) | 14:19 | 32:112 | 12:145 | P < 0.01 |
Operation time (min) (range) | 109 (20-240) | 118 (30-420) | 92 (10-300) | NS |
Severe Fibrosis (%) | 18.1 | 5.5 | 6.3 | P < 0.05 SM:M |
En bloc resection (%) | 90.9 | 90.9 | 89.1 | NS |
Complete resection (%) | 72.7 | 84 | 81.5 | NS |
Perforation (%) | 6 | 7.6 | 1.9 | NS |
Postoperative hemorrhage (%) | 0 | 6.2 | 1.2 | NS |
Table 5 Characteristics of submucosally invasive cancer resected by endoscopic submucosal dissection
SM1 | SM2-3 | Pvalue | |
Number of tumors | 13 | 20 | |
Tumor size (mm) (range) | 30.7 (20-60) | 23.7 (10-60) | NS |
Location | 8:5 | 10:10 | NS |
(colon/ rectum) | |||
Morphology (Is, Isp/ IIa, IIc, IIa + IIc) | 4:9 | 10:10 | NS |
Operation time (min) (range) | 121 (50-240) | 98 (20-230) | NS |
Severe fibrosis (%) | 15.3 | 20 | NS |
En bloc resection (%) | 90.9 | 89.1 | NS |
Venous invasion (%) | 1 (7.6) | 6 (30.0) | NS |
Lymphatic invasion (%) | 2 (15.3) | 4 (20.0) | NS |
Positive of horizontal margin (%) | 3 (23.0) | 3 (15.0) | NS |
Positive of vertical margin (%) | 1 (7.6) | 4 (20.0) | NS |
Perforation (%) | 7.6 | 1.9 | NS |
- Citation: Yoshida N, Naito Y, Yagi N, Yanagisawa A. Importance of histological evaluation in endoscopic resection of early colorectal cancer. World J Gastrointest Pathophysiol 2012; 3(2): 51-59
- URL: https://www.wjgnet.com/2150-5330/full/v3/i2/51.htm
- DOI: https://dx.doi.org/10.4291/wjgp.v3.i2.51