Alcoholic hepatitis: The pivotal role of Kupffer cells

doi:10.4291/wjgp.v6.i4.90

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World Journal of Gastrointestinal Pathophysiology

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2150-5330

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Pathophysiol. Nov 15, 2015; 6(4): 90-98
Published online Nov 15, 2015. doi: 10.4291/wjgp.v6.i4.90

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Figure 1 Central mediating role of Kupffer cells in alcoholic hepatitis. The dysregulation between the pro-inflammatory and the anti-inflammatory cytokines eventually leads to hepatocyte injury. Image components obtained from somersault 1824 online image library (http://www.somersault1824.com/). LPS: Lipopolysaccharides; TLR-4: Toll-like receptor 4; IL: Interleukin; TNF: Tumor necrosis factor; ROS: Reactive oxygen species.

Citation: Suraweera DB, Weeratunga AN, Hu RW, Pandol SJ, Hu R. Alcoholic hepatitis: The pivotal role of Kupffer cells. World J Gastrointest Pathophysiol 2015; 6(4): 90-98
URL: https://www.wjgnet.com/2150-5330/full/v6/i4/90.htm
DOI: https://dx.doi.org/10.4291/wjgp.v6.i4.90