Role of color Doppler in differentiation of Graves' disease and thyroiditis in thyrotoxicosis

Table 1 Comparing parameters between hyperthyroidism and thyroiditis

Parameter	Graves	Thyroiditis	P value
Age, yr (mean ± SD)	31.1 ± 8.4	33.1 ± 7.5	0.565
Thyroid volume (cm3)	24.2 ± 10.1	14.8 ± 7.54	0.028
RPSV (cm/s)	50.4 ± 23.4	21.7 ± 14.8	0.004
REDV (cm/s)	31.3 ± 16.6	12.8 ± 9.4	0.007
RMV (cm/s)	68.9 ± 31.6	30.6 ± 20.3	0.004
LPSV (cm/s)	49 ± 25.7	17.8 ± 6	0.001
LEDV (cm/s)	29.6 ± 17.5	10 ± 4.5	0.001
LMV (cm/s)	68.4 ± 35.2	25.5 ± 8.3	0.001

RPSV: Right peak systolic velocity; REDV: Right end diastolic velocity; RMV: Right man velocity; LPSV: Left peak systolic velocity; LEDV: Left end diastolic velocity; LMV: Left mean velocity (t test).

Table 2 Sensitivity and specificity of color flow Doppler

Parameter	Estimate	Lower-upper 95%CI
Sensitivity	88.9%	67.2-96.9
Specificity	87.5%	52.9-97.8
Positive predictive value	94.1%	73.0-99
Negative predictive value	77.8%	45.3-93.7
Diagnostic accuracy	88.5%	71-96
Likelihood ratio of a positive test	7.1	0.99-51.3
Likelihood ratio of a negative test	0.1	0.05-0.4
Diagnostic odds	56	4.3-724.1
Cohen's kappa (unweighted)	0.7	0.4-1.1