Acquired factor XIII deficiency presenting with multiple intracranial hemorrhages and right hip hematoma: A case report

Table 1 Changes in hemostatic parameters throughout time

FXIII antigen (%)	INR	APTT ratio	Fibrinogen (mg/dL)
Reference ranges	75.2-154.8	0.80-1.20	24.5-31.7	1.80-4.00
At diagnosis	49.2	1.06	29.6	5.3
Last blood sample	37.7	0.98	27.3	5.14

FXIII: Factor XIII; INR: International normalized ratio; APTT: Activated partial thromboplastin time.

Table 2 Blood test

	Patient	Reference ranges
Coagulation-active factor VII (%)	90.8	50-150
Coagulation-active factor VIII (%)	170.7	50-150
Antithrombin III activity (%)	100.5	70-125
Fibrinolytic-antifibrinolytic complex (ng/mL)	1.14	< 0.85
Thrombin regulatory protein antigen (IU/mL)	12.08	3.82-13.35
Platelet count (x109/L)	352	125-350
Protein C activity (%)	104.7	70-140
Protein S Activity (%)	113.5	55-130
IgG (mg/dL)	9.63	8.60-17.40
IgA (mg/dL)	1.94	1.00-4.20
IgM (mg/dL)	0.63	0.30-2.20
C3 (mg/dL)	0.70-1.40	1.1
C4 (mg/dL)	0.10-0.40	0.32