Does sevoflurane sedation in pediatric patients lead to “pseudo” leptomeningeal enhancement in the brain on 3 Tesla magnetic resonance imaging?

Table 1 Means and frequencies of patient age, sex, weight, and sedation duration

Parameter		Mean	SD	Minimum	Maximum	n	%
Age, mo		29.95	25.42	1.00	96.00
Sex	Male					31	49.2
	Female					32	50.8
Weight, kg		12.03	6.25	1.30	26.50
Duration of sedation, min		57.78	24.76	28.00	196.00

SD: Standard deviation.

Table 2 Underlying conditions in the included pediatric patients

Diagnosis	n	%
Atrial septal defect	1	1.6
Autism	1	1.6
Bilateral congenital cataracts	1	1.6
Cerebral palsy	2	3.1
Congenital deafness	1	1.6
Developmental delay	7	11.1
Double aortic arch	1	1.6
Headache	1	1.6
Hypoxic ischemic encephalopathy	2	3.1
Hydrocephalus	3	4.7
Hypotonia	1	1.6
Infantile spasms	1	1.6
Metabolic disorder	2	3.1
Metachromatic leukodystrophy	2	3.1
Not available/none	14	7.9
Nystagmus	1	1.6
Retinal detachment/vitreous hemorrhage	1	1.6
Severe combined immunodeficiency	1	1.6
Seizure disorder	20	31.7

Table 3 Correlation between patient age, weight and duration of sedation with leptomeningeal contrast enhancement grade

Parameter	Spearman’s rank coefficient, P	P value
Age	-0.41	0.011
Weight	-0.42	0.030
Duration of sedation	-0.18	0.142