Retrospective Study
Copyright ©The Author(s) 2022.
World J Radiol. Sep 28, 2022; 14(9): 319-328
Published online Sep 28, 2022. doi: 10.4329/wjr.v14.i9.319
Table 1 Sensitivity, specificity, positive predictive value and negative predictive value per ovarian-adnexal reporting and data system category for each reader on the pre-training assessment
Pre training
ORADS 1, %
ORADS 2, %
ORADS 3, %
ORADS 4, %
ORADS 5, %
Sensitivity
R190 (55.5 to 99.8)100 (69.5 to 100)100 (59.0 to 100)92 (61.5 to 99.8)55 (23.4 to 83.3)
R290% (55.5 to 99.8)100% (69.2 to 100)71 (29.0 to 96.3)92 (61.5 to 99.8)82 (48.2 to 97.7)
R390 (55.5 to 99.8)100 (69.2 to 100)100 (59.0 to 100)75 (42.8 to 94.5) 55 (23.4 to 83.3)
Specificity
R1100 (91.2 to 100)85 (70.2 to 94.3)98 (87.7 to 99.4)100 (90.8 to 100)100 (91.0 to 100)
R2100 (91.2 to 100)90 (76.3 to 97.2)98 (87.7 to 99.4)97 (86.2 to 99.9)100 (91.0 to 100)
R398 (86.8 to 99.9)90 (76.3 to 97.2)95 (84.2 to 99.4)95 (82.3 to 99.4)100 (91.0 to 100)
PPV
R110063 (44.4 to 77.7)88 (50.2 to 98.0)100100
R210071 (49.7 to 86.4)83 (40.5 to 97.4)92 (61.2 to 98.7)100
R390 (56.2 to 98.4)71 (49.7 to 86.4)78 (47.5 to 93.1)82 (52.9 to 94.8)100
NPV
R198 (86.2 to 99.6)10010097 (85.3 to 99.6)89 (80.3 to 93.7)
R298 (86.2 to 99.6)10096 (86.7 to 98.6)97 (85.0 to 99.6)95 (84.8 to 98.6)
R398 (85.9 to 99.6)10010093 (81.8 to 97.0)89 (80.3 to 93.7)
Table 2 The sensitivity, specificity, positive predictive value and negative predictive value per Ovarian-Adnexal Reporting and Data System category for each reader on the post-training assessment
Post training
ORADS 1, %
ORADS 2, %
ORADS 3, %
ORADS 4, %
ORADS 5, %
Sensitivity
R1100 (69.2 to 100)100 (69.2 to 100)100 (59 to 100)92 (61.5 to 99.8)73 (39 to 94)
R290 (55.5 to 99.8)90 (55.5 to 99.8)86 (42.1 to 99.6)92 (61.5 to 99.8)82 (48.2 to 97.7)
R3100 (69.2 to 100)100 (69.2 to 100)100 (59 to 100)75 (42.8 to 94.5) 64 (30.8 to 89.1)
Specificity
R1100 (91.2 to 100)95 (83.1 to 99.4)98 (87.7 to 99.9)97 (86.2 to 99.9)100 (91 to 100)
R2100 (91.2 to 100)98 (86.8 to 99.9)93 (80.9 to 98.5)95 (82.3 to 99.4)100 (91 to 100)
R3100 (91.2 to 100)95 (83.1 to 99.4)91 (77.9 to 97.4)97 (86.2 to 99.9)100 (91 to 100)
PPV
R110083 (56.4 to 95.1)88 (50.2 to 98)92 (61.2 to 98.7)100
R210090 (56.2 to 98.4)67 (39.2 to 86.1)85 (58.5 to 95.5)100
R310083 (56.4 to 95.1)64 (40.8 to 81.7)90 (55.9 to 98.5)100
NPV
R110010010097 (85 to 99.6)93 (83.2 to 97.2)
R298 (86.2 to 99.6)98 (85.9 to 99.6)98 (86.7 to 99.6)97 (84.6 to 99.6)95 (84.8 to 98.6)
R310010010093 (82.2 to 97.1)91 (81.7 to 95.5)
Table 3 Misclassified ovarian-adnexal reporting and data system categories by readers in pre-training and post-training assessment
ORADS categoryReference standard lexicon descriptorMisclassification categoryReader lexicon descriptorFrequency of error in pre-trainingFrequency of error in post-training
ORADS 1Follicle defined as a simple cyst ≤ 3 cmORADS 2Follicle defined as a simple cyst ≤ 3 cm11
Follicle defined as a simple cyst ≤ 3 cmORADS 2Simple cyst > 5 cm but < 10 cm10
Follicle defined as a simple cyst ≤ 3 cmORADS 3Multilocular cyst with smooth inner walls/septations < 10 cm, CS1-310
ORADS 2simple cyst > 3 cm to 5 cmORADS 3Unilocular cyst with irregular inner wall < 3mm height, any size01
ORADS 3Multilocular cyst with smooth inner walls/septations, < 10 cm, CS1-3ORADS 2Simple cyst > 5 cm but < 10 cm10
Multilocular cyst with smooth inner walls/septations, < 10 cm, CS1-3ORADS 4Multilocular cyst, irregular inner wall ± irregular septation01
Unilocular cyst (simple or non-simple) ≥ 10 cmORADS 4Unilocular cyst with 1-3 papillary projections10
ORADS 4Multilocular cyst, irregular inner wall ± irregular septationORADS 1Follicle defined as a simple cyst ≤ 3 cm10
Multilocular cyst, irregular inner wall ± irregular septationORADS 2Classic benign lesion (hemorrhagic cyst < 10 cm)10
Multilocular cyst, irregular inner wall ± irregular septationORADS 3Typical dermoid cyst, endometrioma, hemorrhagic cyst ≥ 10 cm01
Multilocular cyst, irregular inner wall ± irregular septationORADS 3Multilocular cyst with smooth inner walls/septations < 10 cm, CS1-334
ORADS 5Solid lesion with irregular outer contourORADS 2Classic benign lesion (dermoid cyst < 10 cm)104
Solid lesion with irregular outer contourORADS 3Solid lesion with smooth outer contour, any size, CS = 101
Solid lesion with irregular outer contourORADS 3Typical dermoid cyst, endometrioma, hemorrhagic cyst ≥ 10 cm01
Solid lesion with irregular outer contourORADS 4Unilocular cyst with solid component11
Solid lesion with irregular outer contourORADS 4Solid lesion with smooth outer contour, any size, CS = 2-302
Multilocular cyst with solid component, CS3-4ORADS 4Multilocular cyst with solid component, CS1-210