Echographic imaging of tumoral cells through novel nanosystems for image diagnosis

Figure 1 Echographic detection of silica nanoparticles. Sample pictures and corresponding echographic images of pure agarose gel (A) and 330 nm nanoparticle-containing gel (B).

Figure 2 Effect of polyethylene glycol coating on silica nanoparticle biocompatibility. MCF-7 cells were incubated for 72 h in the presence of indicated concentrations of uncoated (A) or polyethylene glycol-coated (B) silica nanoparticles (SiNP).

Figure 3 Morphological and echographic characterization of dual mode silica nanoparticles. A-C: Transmission electron microscopy and (D-F) corresponding ultrasound images of uncoated (A, D), IO-coated (B, E) and FePt-IO-coated (C, F) 330 nm silica nanoparticles; G: Image of pure agarose gel (negative control).

Figure 4 Ultrasound detection of halloysite clay nanotube. A: Gel sample echographic images of pure and agarose containing halloysite clay nanotube (HNT) at the indicated concentrations; B: Quantitative analysis of backscattered signal as a function of ultrasonic frequency and HNT concentration. SER: Signal enhancement ratio; CoFI: Contribution of frequency increment.