Coronary artery calcium score on low-dose computed tomography for lung cancer screening

Figure 1 Coronary artery calcium score values. The Figure shows the mean and median values of Volume, Mass, and Agatston Score for gCCT and ngCCT in the total population. There is a sharp tendency to underestimate of ngCCT for all types of CACS score. gCCT: ECG gated cardiac computed tomography; ngCCT: Non-gated chest computed tomography; CACS: Coronary artery calcium score.

Figure 2 Scatter plots coronary artery calcium score values. The scatter plots show the high correlation of Volume (A), Mass (B), and Agatston (C) scores obtained with gCCT and ngCCT. gCCT: ECG gated cardiac computed tomography; ngCCT: Non-gated chest computed tomography.

Figure 3 Bland-Altman plots of coronary artery calcium score values. The Bland-Altman plots show the slight but significant tendency to overestimate Volume (A), Mass (B), and Agatston (C) scores of ngCCT as compared to gCCT. There are 2 patients with values far off in ngCCT vs gCCT. However, they are both with very high values and this does not affect significantly further reclassification. gCCT: ECG gated cardiac computed tomography; ngCCT: Non-gated chest computed tomography.

Figure 4 Restratification. The Figure shows the pattern of reclassification of cardiovascular risk categories using the Mayo Clinic Classification (Rumberger et al) with gCCT and ngCCT within the same population (CACS score according to Agatston). ngCCT determines a shift in the ranges between 1 and 400 Agatston score. Some of these patients shift to a lower category (in particular the ones with Agatston score between 1 and 10), while some of the patients shifts towards higher risk categories (in particular the ones with Agatston score between 11 and 100). In total 23 patients shifted to another cardiovascular risk category in ngCCT. gCCT: ECG gated cardiac computed tomography; ngCCT: Non-gated chest computed tomography; CACS: Coronary artery calcium score.