Bilateral primary xanthoma of the humeri with pathologic fractures: A case report

Figure 1 Anteroposterior radiographs of the humeri, showing bilateral proximal humeral pathologic fractures and underlying aggressive appearing ill-defined permeative lytic lesions, more pronounced in the right humerus.

Figure 2 Positron emission tomography-computed tomography. A: Axial PET image of the bilateral proximal humeral bones, showing increased uptake of F-18 FDG (arrows) in and adjacent to the fractures; B: Demonstrated on the corresponding CT image (arrowheads). PET: Positron emission tomography; FDG: Fluorodeoxyglucose; CT: Computed tomography.

Figure 3 Positron emission tomography-computed tomography. A: Axial PET image of the proximal right femur, showing increased uptake of F-18 FDG; B: Corresponding CT with morphologically normal proximal right femur. PET-CT: Positron emission tomography-computed tomography.

Figure 4 Hematoxylin and eosin stained image (× 125 magnification). The biopsy specimen demonstrating foamy lipidic histiocytic infiltration (arrow) of marrow; Trabeculae are noted (arrowheads).

Figure 5 Lesion was excised, and a long stemmed proximal humerus modular endoprosthesis was inserted.