Spectral computed tomography parameters of primary tumors and lymph nodes for predicting tumor deposits in colorectal cancer

Figure 1 Flowchart of the patient recruitment process. TDs: Tumor deposits.

Figure 2 Illustration of venous phase segmentation. The 74-year-old male patient with tumor deposits+. In the arterial and venous phases, the normalized iodine concentration of region of interest. A: Primary tumors (arrow) = 0.16, 0.49; B: The largest regional lymph nodes (dashed arrow) = 0.17, 0.48. Lymph node-to-primary tumor ratio = 1.09, 0.98.

Figure 3 Illustration of venous phase segmentation. The 66-year-old male patient with tumor deposits-. In the arterial and venous phases the normalized iodine concentration of region of interest: A: Primary tumors (arrow) = 0.14, 0.38; B: The largest regional lymph nodes (dashed arrow) = 0.20, 0.65. Lymph node-to-primary tumor ratio = 1.39, 1.73.

Figure 4 Receiver operating characteristic curves of the quantitative parameters used for the differential diagnosis of tumor deposits+ and tumor deposits- patients. The areas under the curve of arterial phase-normalized iodine concentration-lymph node-to-primary tumor ratio was the highest at 0.812 (sensitivity: 0.879, specificity: 0.648, cutoff value: 1.145). AP: Arterial phase; VP: Venous phase; NIC: Normalized iodine concentration; LN: Lymph node; T: Primary tumor; NTR: Lymph node-to-primary tumor ratio.