Effect of varying computed tomography acquisition and reconstruction parameters on semi-automated clot volume quantification

Figure 1 Photograph of 10 blood clot phantom (A); Volume rendered 3D reconstructed CT image of 10 blood clot phantom (B); Coronal CT images of ten blood clot phantom showing in (C) clots numbered 4, 6, 8 and 10, in (D) clots numbered 3, 5, and 7 and in (E) clots numbered 1, 2 and 9.

Figure 2 Box plots showing the difference between the segmented volume and the mean measured (gold standard) volume for Clot 10 as it relates to the following acquisition and reconstruction parameters. A: Energy and pitch; B: Energy and slice thickness; C: Slice thickness and pitch; D: Energy and Siemens Advanced Modeled Iterative Reconstruction (ADMIRE); E: Pitch and ADMIRE; F: Slice thickness and ADMIRE.

Figure 3 Correlation between scale measured mass vs computed tomography acquired volume of 10 clots with an excellent R² correlation value of 0. 9956.

Figure 4 Correlation between scale measured mass vs volume by physical measurement (cm³) (average of 5 measurements) of 10 clots with an excellent R² correlation value of 0. 9987.