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For: Nambu A, Ozawa K, Kobayashi N, Tago M. Imaging of community-acquired pneumonia: Roles of imaging examinations, imaging diagnosis of specific pathogens and discrimination from noninfectious diseases. World J Radiol 2014; 6(10): 779-793 [PMID: 25349662 DOI: 10.4329/wjr.v6.i10.779]
URL: https://www.wjgnet.com/1949-8470/full/v6/i10/779.htm
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Fattane Shirani, Azin Shayganfar, Somayeh Hajiahmadi. COVID-19 pneumonia: a pictorial review of CT findings and differential diagnosisEgyptian Journal of Radiology and Nuclear Medicine 2021; 52(1) doi: 10.1186/s43055-021-00415-2
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Hyewon Seo, Seung-Ick Cha, Kyung-Min Shin, Jae-Kwang Lim, Seung-Soo Yoo, Shin-Yup Lee, Jaehee Lee, Chang-Ho Kim, Jae-Yong Park. Relationship Between Clinical Features and Computed Tomographic Findings in Hospitalized Adult Patients With Community-Acquired PneumoniaThe American Journal of the Medical Sciences 2018; 356(1): 30 doi: 10.1016/j.amjms.2018.03.024
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Hye Rim Park, Young Tong Kim, Sung Shick Jou, Chan Ho Park. Pulmonary Comorbidities of Lung EmphysemaJournal of the Korean Society of Radiology 2018; 79(3): 139 doi: 10.3348/jksr.2018.79.3.139
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Brian P. Pogatchnik, Wakana Murakami, Shabnam Mortazavi. Coronavirus Disease 2019 (COVID‐19)2023; : 61 doi: 10.1002/9781119789741.ch4
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Marc Garnier, El Mahdi Hafiani, Charlotte Arbelot, Clarisse Blayau, Vincent Labbe, Katia Stankovic-Stojanovic, François Lionnet, Francis Bonnet, Jean-Pierre Fulgencio, Muriel Fartoukh, Christophe Quesnel. Morpho-functional evaluation of lung aeration as a marker of sickle-cell acute chest syndrome severity in the ICU: a prospective cohort studyAnnals of Intensive Care 2019; 9(1) doi: 10.1186/s13613-019-0583-y
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Dinesh Singh. Thoracic Imaging2019; : 147 doi: 10.1007/978-981-13-2544-1_6
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Donato Lacedonia, Carla Maria Irene Quarato, Cristina Borelli, Lucia Dimitri, Paolo Graziano, Maria Pia Foschino Barbaro, Giulia Scioscia, Antonio Mirijello, Michele Maria Maggi, Gaetano Rea, Beatrice Ferragalli, Salvatore De Cosmo, Marco Sperandeo. Transthoracic Ultrasound in Infectious Organizing Pneumonia: A Useful Guide for Percutaneous Needle BiopsyFrontiers in Medicine 2021; 8 doi: 10.3389/fmed.2021.708937
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Bahman Rasuli, Ian Bickle. Radiopaedia.org2015;  doi: 10.53347/rID-38761
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Kehkashan Kanwal, Muhammad Asif, Syed Ghufran Khalid, Haipeng Liu, Aisha Ghazal Qurashi, Saad Abdullah. Current Diagnostic Techniques for Pneumonia: A Scoping ReviewSensors 2024; 24(13): 4291 doi: 10.3390/s24134291
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Canbahar Sezgin, Muge Gunalp, Sinan Genc, Nurdan Acar, Evren Ustuner, Ahmet Burak Oguz, Ayca Koca Tanriverdi, Arda Demirkan, Onur Polat. Diagnostic Value of Bedside Lung Ultrasonography in PneumoniaUltrasound in Medicine & Biology 2020; 46(5): 1189 doi: 10.1016/j.ultrasmedbio.2020.01.014
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Katya Rozovsky, Martin Bunge, Rick Higgins, Raquel Consunji-Araneta, Lina Alqublan, Sergio Fanella. Imaging Patterns of Pediatric Pulmonary BlastomycosisAmerican Journal of Roentgenology 2019; 212(4): 905 doi: 10.2214/AJR.18.19811
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Anand Thyagachandran, Hema A Murthy. Ensemble Methods For Enhanced Covid-19 CT Scan Severity Analysis2023 IEEE International Conference on Acoustics, Speech, and Signal Processing Workshops (ICASSPW) 2023; : 1 doi: 10.1109/ICASSPW59220.2023.10193538
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Justin L. Wong, Scott E. Evans. Bacterial Pneumonia in Patients with CancerClinics in Chest Medicine 2017; 38(2): 263 doi: 10.1016/j.ccm.2016.12.005
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Emmanuel Ledoult, Maxime Morelle, Michael Soussan, Arsène Mékinian, Hélène Béhal, Vincent Sobanski, Eric Hachulla, Damien Huglo, Noémie Le Gouellec, Martine Remy-Jardin, Clio Baillet, David Launay. 18F-FDG positron emission tomography scanning in systemic sclerosis-associated interstitial lung disease: a pilot studyArthritis Research & Therapy 2021; 23(1) doi: 10.1186/s13075-021-02460-8
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Feng Chen, Meiji Ren, Hongjun Li. Radiology of Influenza2016; : 23 doi: 10.1007/978-94-024-0908-6_8
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Priya Sawant, R. Sreemathy. Advanced Machine Intelligence and Signal ProcessingLecture Notes in Electrical Engineering 2022; 858: 707 doi: 10.1007/978-981-19-0840-8_55
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Shan Huang, Yuan-Cheng Wang, Shenghong Ju. Advances in medical imaging to evaluate acute respiratory distress syndromeChinese Journal of Academic Radiology 2022; 5(1): 1 doi: 10.1007/s42058-021-00078-y
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Sara Besharat, Fatemehsadat Rahimi, Siamak Afaghi, Farzad Esmaeili Tarki, Fatemeh Pourmotahari, Mohammad Fathi, Alireza Zali, Morteza Sanei Taheri, Hossein Ghanaati, Nasser Malekpour Alamdari. Chest CT Imaging Characteristics of COVID-19 Pneumonia in Surviving and Non-surviving Hospitalized Patients: A Retrospective Study in a Referral Center in Tehran, IranIranian Journal of Radiology 2021; 18(2) doi: 10.5812/iranjradiol.106339
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Anand Thyagachandran, Aathira Balachandran, Hema A. Murthy. Identification and Severity Assessment of COVID-19 Using Lung CT ScansIEEE Access 2023; 11: 124542 doi: 10.1109/ACCESS.2023.3330238
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Fumihiro Ogawa, Hideaki Kato, Kento Nakajima, Tomoki Nakagawa, Reo Matsumura, Yasufumi Oi, Kazuya Sakai, Munehito Uchiyama, Yutaro Ohyama, Takeru Abe, Ichiro Takeuchi. Therapeutic strategy for severe COVID-19 pneumonia from clinical experienceEuropean Journal of Inflammation 2020; 18: 205873922096159 doi: 10.1177/2058739220961591
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Shengyi Li, Yue Hu, Lexin Yang, Baohua Lv, Xue Kong, Guangliang Qiang. DSEception: a noval neural networks architecture for enhancing pneumonia and tuberculosis diagnosisFrontiers in Bioengineering and Biotechnology 2024; 12 doi: 10.3389/fbioe.2024.1454652
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Fernando Almeida-Siva, Rodrigo Almeida-Paes , Lisandra Serra-Damasceno , Edwiges Motta-Santos , Luiz Claudio Ferreira, Leonardo Pereira-Quintella, Marcela De Faria Ferreira , Mauro De Medeiros-Muniz , Rosely M. Zancopé-Oliveira . The conventional diagnosis challenge: Real-time PCR and nested PCR correlation with the scoring system for individuals at high-risk of Pneumocystis jirovecii pneumoniaBiomédica 2023; 43(Sp. 1): 255 doi: 10.7705/biomedica.7020
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Tiantian Yin, Juan Han, Jinjin Hao, Hui Yu, Yining Qiu, Jiawei Xu, Yun Peng, Xiaoyan Wu, Runming Jin, Fen Zhou. Clinical characteristics and risk factors of acute lymphoblastic leukemia in children with severe infection during maintenance treatmentCancer Medicine 2023; 12(19): 19372 doi: 10.1002/cam4.6495
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Jinkui Hao, Jianyang Xie, Ri Liu, Huaying Hao, Yuhui Ma, Kun Yan, Ruirui Liu, Yalin Zheng, Jianjun Zheng, Jiang Liu, Jingfeng Zhang, Yitian Zhao. Automatic Sequence-Based Network for Lung Diseases Detection in Chest CTFrontiers in Oncology 2021; 11 doi: 10.3389/fonc.2021.781798
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Mandeep Garg, Nidhi Prabhakar, P. Kiruthika, Ritesh Agarwal, Ashutosh Aggarwal, Ajay Gulati, Niranjan Khandelwal. Imaging of Pneumonia: An OverviewCurrent Radiology Reports 2017; 5(4) doi: 10.1007/s40134-017-0209-9
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Qianye Zhao, Teng Zhang, Beibei Zhu, Ying Bi, Shi-Wen Jiang, Yifan Zhu, Deyu Zhao, Feng Liu. Increasing Age Affected Polymorphonuclear Neutrophils in Prognosis of Mycoplasma pneumoniae PneumoniaJournal of Inflammation Research 2021; : 3933 doi: 10.2147/JIR.S321656
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Hyewon Seo, Seung-Ick Cha, Kyung-Min Shin, Jae-Kwang Lim, Seung-Soo Yoo, Shin-Yup Lee, Jaehee Lee, Chang-Ho Kim, Jae-Yong Park. Community-Acquired Pneumonia with Negative Chest Radiography Findings: Clinical and Radiological FeaturesRespiration 2019; 97(6): 508 doi: 10.1159/000495068
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Ala Eddin S. Sagar, Scott E. Evans. Oncologic Critical Care2020; : 607 doi: 10.1007/978-3-319-74588-6_53
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Shivanthan Shanthikumar, Amelia Clifford, John Massie, Theresa Cole, Andrew Steer, Michael Marks, Amanda Gwee. Community-acquired pneumonia in children: what to do when there is no response to standard empirical treatment?Thorax 2016; 71(10): 957 doi: 10.1136/thoraxjnl-2016-208787
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J.J. Arenas-Jiménez, J.M. Plasencia-Martínez, E. García-Garrigós. When pneumonia is not COVID-19Radiología (English Edition) 2021; 63(2): 180 doi: 10.1016/j.rxeng.2020.11.003
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Harshal A. Sanghvi, Riki H. Patel, Ankur Agarwal, Shailesh Gupta, Vivek Sawhney, Abhijit S. Pandya. A deep learning approach for classification of COVID and pneumonia using DenseNet‐201International Journal of Imaging Systems and Technology 2023; 33(1): 18 doi: 10.1002/ima.22812
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Sunil Diwate, D. Nema, Arun Kumar Yadav. Role of Chemoprophylaxis in Outbreak Control of Pneumonia in an Institutional SettingJournal of Marine Medical Society 2024; 26(1): 53 doi: 10.4103/jmms.jmms_189_22
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Philip Goodman, Helmut Prosch, Christian J. Herold. Diseases of the Chest and Heart 2015–20182015; : 63 doi: 10.1007/978-88-470-5752-4_8
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Daria Manos. Errors in Emergency and Trauma Radiology2019; : 83 doi: 10.1007/978-3-030-05548-6_5
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J.J. Arenas-Jiménez, J.M. Plasencia-Martínez, E. García-Garrigós. Cuando la neumonía no es COVID-19Radiología 2021; 63(2): 180 doi: 10.1016/j.rx.2020.11.003
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Rokaya Rehouma, Michael Buchert, Yi‐Ping Phoebe Chen. Machine learning for medical imaging‐based COVID‐19 detection and diagnosisInternational Journal of Intelligent Systems 2021; 36(9): 5085 doi: 10.1002/int.22504
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Weixiang Chen, Jianjiang Feng, Jie Zhou. TriageNet: A Multi-Agent Diagnosis Network for Imbalanced Data2022 IEEE 19th International Symposium on Biomedical Imaging (ISBI) 2022; : 1 doi: 10.1109/ISBI52829.2022.9761420
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Yalong Yang, Yuexuan Wu, Wen Zhao. Comparison of lung ultrasound and chest radiography for detecting pneumonia in children: a systematic review and meta-analysisItalian Journal of Pediatrics 2024; 50(1) doi: 10.1186/s13052-024-01583-3
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An-Fu Lee, Hong-Wei Lee, Zui-Shen Yen. Persistent hiccups as a rare presenting symptom of empyema: a case reportInternational Journal of Emergency Medicine 2024; 17(1) doi: 10.1186/s12245-024-00603-7
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Maki Miwa, Mikio Nakajima, Hideaki Goto. Peripheral “Swiss Cheese” Appearance in a COVID-19 Patient with Chronic Obstructive Pulmonary Disease The American Journal of Tropical Medicine and Hygiene 2020; 103(2): 546 doi: 10.4269/ajtmh.20-0605
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Mahmoud M.S. Elsayed, Hossam A. El Hafez Zayton, Mohamed S. Hantera, Fatma A. Elshaarawy. Role of multislice computed tomography in evaluation of thoracic complications in patients with chronic renal failureTanta Medical Journal 2021; 49(2): 121 doi: 10.4103/tmj.tmj_33_20
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Ali H. Elmokadem, Nihal M. Batouty, Dalia Bayoumi, Basma N. Gadelhak, Rihame M. Abdel-Wahab, Mona Zaky, Sherif A. Abo-Hedibah, Ahmed Ehab, Ahmed El-Morsy. Mimickers of novel coronavirus disease 2019 (COVID-19) on chest CT: spectrum of CT and clinical featuresInsights into Imaging 2021; 12(1) doi: 10.1186/s13244-020-00956-6
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Yuichiro Ozawa, Kazunori Kamiya, Hiroichi Ishikawa, Mitsuaki Sakai. A Case of T4 Lung Adenocarcinoma with Slow Spreading Airspace ConsolidationHaigan 2020; 60(7): 1001 doi: 10.2482/haigan.60.1001
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E. Ledoult, C. Baillet, V. Sobanski, P.Y. Hatron, E. Hachulla, D. Launay. Fixation au TEP-scan d’une pneumopathie interstitielle diffuse associée à la sclérodermie systémiqueLa Revue de Médecine Interne 2016; 37: A92 doi: 10.1016/j.revmed.2016.04.021
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P. Lewis White, Matthijs Backx, Rosemary A. Barnes. Diagnosis and management ofPneumocystis jiroveciiinfectionExpert Review of Anti-infective Therapy 2017; 15(5): 435 doi: 10.1080/14787210.2017.1305887
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Ala Eddin S. Sagar, Scott E. Evans. Oncologic Critical Care2019; : 1 doi: 10.1007/978-3-319-74698-2_53-1
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Bei Wang, Min Li, He Ma, Fangfang Han, Yan Wang, Shunying Zhao, Zhimin Liu, Tong Yu, Jie Tian, Di Dong, Yun Peng. Computed tomography-based predictive nomogram for differentiating primary progressive pulmonary tuberculosis from community-acquired pneumonia in childrenBMC Medical Imaging 2019; 19(1) doi: 10.1186/s12880-019-0355-z
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Shuichi Fukui, Ryoko Egashira, Ken Yamaguchi, Takahiko Nakazono, Ryota Sakurai, Miho Asahi, Hiroyuki Irie. A Case of Fulminant Invasive Pneumococcal Disease With Unique Diffuse Pulmonary Lesions on Thin-section Computed TomographyJournal of Thoracic Imaging 2020; 35(6): W127 doi: 10.1097/RTI.0000000000000555
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Durgesh K. Dwivedi, Anit Parihar, Neera Kohli, Himanshu R. Dandu, Shailendra K. Saxena. Diagnostic Strategies for COVID-19 and other CoronavirusesMedical Virology: From Pathogenesis to Disease Control 2020; : 37 doi: 10.1007/978-981-15-6006-4_3
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Weixiang Chen, Xiaoyu Han, Jian Wang, Yukun Cao, Xi Jia, Yuting Zheng, Jie Zhou, Wenjuan Zeng, Lin Wang, Heshui Shi, Jianjiang Feng. Deep diagnostic agent forest (DDAF): A deep learning pathogen recognition system for pneumonia based on CTComputers in Biology and Medicine 2022; 141: 105143 doi: 10.1016/j.compbiomed.2021.105143
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Luyao Ma, Yun Wang, Lin Guo, Yu Zhang, Ping Wang, Xu Pei, Lingjun Qian, Stefan Jaeger, Xiaowen Ke, Xiaoping Yin, Fleming Y.M. Lure. Developing and verifying automatic detection of active pulmonary tuberculosis from multi-slice spiral CT images based on deep learningJournal of X-Ray Science and Technology 2020; 28(5): 939 doi: 10.3233/XST-200662
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Gina Amanda, Wisnu Tafroji, Dianiati Kusumo Sutoyo, Erlina Burhan, Budi Haryanto, Dodi Safari. Serotype distribution and antimicrobial profile of Streptococcus pneumoniae isolated from adult patients with community-acquired pneumonia in Jakarta, IndonesiaJournal of Microbiology, Immunology and Infection 2021; 54(6): 1175 doi: 10.1016/j.jmii.2020.10.003
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Jiyoon Kang, Subba R. Digumarthy. Imaging in Lung TransplantationRadiologic Clinics of North America 2023; 61(5): 833 doi: 10.1016/j.rcl.2023.04.006
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Shekhar Kunal, Vikas Pilaniya, Sudhir Jain, Ashok Shah. ‘Crazy-paving’ pattern: an exceptional presentation of cryptogenic organising pneumonia associated with chronic obstructive pulmonary diseaseBMJ Case Reports 2016; : bcr2016215445 doi: 10.1136/bcr-2016-215445
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Leonid Roshkovan, Neil Chatterjee, Maya Galperin-Aizenberg, Narainder Gupta, Rosita Shah, Eduardo Mortani Barbosa, Scott Simpson, Tessa Cook, Arun Nachiappan, Friedrich Knollmann, Harold Litt, Benoit Desjardins, Saurabh Jha, Nova Panebianco, Cameron Baston, Jeffrey C. Thompson, Sharyn I. Katz. The Role of Imaging in the Management of Suspected or Known COVID-19 Pneumonia. A Multidisciplinary PerspectiveAnnals of the American Thoracic Society 2020; 17(11): 1358 doi: 10.1513/AnnalsATS.202006-600FR
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Vojko Berce, Maja Tomazin, Mario Gorenjak, Tadej Berce, Barbara Lovrenčič. The Usefulness of Lung Ultrasound for the Aetiological Diagnosis of Community-Acquired Pneumonia in ChildrenScientific Reports 2019; 9(1) doi: 10.1038/s41598-019-54499-y
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Lanhua Zhang, Shixiong Qiu, Cui Tang, Jinming Xu. Adult community-acquired pneumonia with unusually enlarged mediastinal lymph nodes: A case reportExperimental and Therapeutic Medicine 2017; 14(1): 87 doi: 10.3892/etm.2017.4449
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Sudipto Saha, Sreyashi Majumdar, Parthasarathi Bhattacharyya. Pulmonomics: Omics Approaches for Understanding Pulmonary Diseases2023; : 331 doi: 10.1007/978-981-99-3505-5_14
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Bin Cao, Yi Huang, Dan‐Yang She, Qi‐Jian Cheng, Hong Fan, Xin‐Lun Tian, Jin‐Fu Xu, Jing Zhang, Yu Chen, Ning Shen, Hui Wang, Mei Jiang, Xiang‐Yan Zhang, Yi Shi, Bei He, Li‐Xian He, You‐Ning Liu, Jie‐Ming Qu. Diagnosis and treatment of community‐acquired pneumonia in adults: 2016 clinical practice guidelines by the Chinese Thoracic Society, Chinese Medical AssociationThe Clinical Respiratory Journal 2018; 12(4): 1320 doi: 10.1111/crj.12674
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Neetu Talwar, Lucky Manik, Krishan Chugh. Pediatric Lung Ultrasound (PLUS) in the diagnosis of Community-Acquired Pneumonia (CAP) requiring hospitalizationLung India 2022; 39(3): 267 doi: 10.4103/lungindia.lungindia_284_21
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Takashi Ishiguro, Yutaka Yoshii, Tetsu Kanauchi, Toshiko Hoshi, Yotaro Takaku, Naho Kagiyama, Kazuyoshi Kurashima, Noboru Takayanagi. Re-evaluation of the etiology and clinical and radiological features of community-acquired lobar pneumonia in adultsJournal of Infection and Chemotherapy 2018; 24(6): 463 doi: 10.1016/j.jiac.2018.02.001
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Dong Han, Taiping He, Yong Yu, Youmin Guo, Yibing Chen, Haifeng Duan, Nan Yu. Diagnosis of Active Pulmonary Tuberculosis and Community Acquired Pneumonia Using Convolution Neural Network Based on Transfer LearningAcademic Radiology 2022; 29(10): 1486 doi: 10.1016/j.acra.2021.12.025
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Dong Han, Yibing Chen, Xuechao Li, Wen Li, Xirong Zhang, Taiping He, Yong Yu, Yuequn Dou, Haifeng Duan, Nan Yu. Development and validation of a 3D-convolutional neural network model based on chest CT for differentiating active pulmonary tuberculosis from community-acquired pneumoniaLa radiologia medica 2022;  doi: 10.1007/s11547-022-01580-8
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Kosaku Komiya, Mari Yamasue, Akihiko Goto, Yuta Nakamura, Kazufumi Hiramatsu, Jun-ichi Kadota, Seiya Kato. High-resolution computed tomography features associated with differentiation of tuberculosis among elderly patients with community-acquired pneumonia: a multi-institutional propensity-score matched studyScientific Reports 2022; 12(1) doi: 10.1038/s41598-022-11625-7
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Yeo Ryang Kang, Yoon Ki Cha, Jeung Sook Kim, Eun Kyoung Lee, Jin Young Oh, So Hyeon Bak, Hyun Jung Yoon. Imaging findings of Stenotrophomonas maltophilia pneumonia: emphasis on CT findings between immunocompromised and immunocompetent patientsActa Radiologica 2020; 61(7): 903 doi: 10.1177/0284185119885117
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Muhammad Waseem Aslam, Seng Fong Lau, Rozanaliza Radzi, Sharina Omar, Ubedullah Kaka, Ishtiaq Ahmed. Clinicopathological and Radiological Features of Cats Presented with Infectious Respiratory Disease Signs: A Focus on Rhodococcus equi and Klebsiella pneumoniaeMicroorganisms 2023; 11(3): 737 doi: 10.3390/microorganisms11030737
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Yuan Lin, Zhuozhi Liang, Xingshan Cai, Yang Luo, Bitong Wu, Yongzhong Feng, Zhiqun Cai, Xiaopeng Liang, Shouyong Tan. Dynamic changes of respiratory microbiota associated with treatment outcome in drug-sensitive and drug-resistant pulmonary tuberculosisAnnals of Clinical Microbiology and Antimicrobials 2024; 23(1) doi: 10.1186/s12941-024-00742-y
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Mariana R. DeFreitas, Holman Page McAdams, Hakim Azfar Ali, Arya M. Iranmanesh, Hamid Chalian. Complications of Lung Transplantation: Update on Imaging Manifestations and ManagementRadiology: Cardiothoracic Imaging 2021; 3(4): e190252 doi: 10.1148/ryct.2021190252
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Wenli Qiu, Haibin Chen, Jian Zhang, Ren Shuai, Huifeng Zhang, Kai Guo, Li Zhu, Zhongqiu Wang. Evaluation of HRCT for the Differential Diagnosis of Pneumonia-Like Consolidation Pattern of Pulmonary MALT Lymphoma from Lobar PneumoniaCancer Management and Research 2021; : 7813 doi: 10.2147/CMAR.S327846
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Abdullah Chahin, Steven M. Opal. Severe Pneumonia Caused by Legionella pneumophilaInfectious Disease Clinics of North America 2017; 31(1): 111 doi: 10.1016/j.idc.2016.10.009
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Keiji Sugishita, Toshiaki Saito, Yukino Asayama, Takashi Iwamoto. Risk factors for detection failures of chest radiography in diagnosing pneumoniaJournal of General and Family Medicine 2017; 18(6): 398 doi: 10.1002/jgf2.111
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Francisco Javier Candel, Miguel Salavert, Miren Basaras, Marcio Borges, Rafael Cantón, Emilia Cercenado, Catian Cilloniz, Ángel Estella, Juan M. García-Lechuz, José Garnacho Montero, Federico Gordo, Agustín Julián-Jiménez, Francisco Javier Martín-Sánchez, Emilio Maseda, Mayra Matesanz, Rosario Menéndez, Manuel Mirón-Rubio, Raúl Ortiz de Lejarazu, Eva Polverino, Pilar Retamar-Gentil, Luis Alberto Ruiz-Iturriaga, Susana Sancho, Leyre Serrano. Ten Issues for Updating in Community-Acquired Pneumonia: An Expert ReviewJournal of Clinical Medicine 2023; 12(21): 6864 doi: 10.3390/jcm12216864